Hepatite granulomatosa em bovino causada por Mycobacterium avium subsp. paratuberculosis / Granulomatous hepatitis in cattle caused by Mycobacterium avium subsp. paratuberculosis

dc.creatorRodrigues, A. B. F
dc.creatorRistow, Paula
dc.creatorSantos, A. S. O
dc.creatorLilenbaum, W
dc.creatorFonseca, L. S
dc.creatorCarvalho, C. B
dc.creatorCarvalho, E. C. Q
dc.date2012-12-20T20:37:23Z
dc.date2012-12-20T20:37:23Z
dc.date2010
dc.date.accessioned2023-09-26T23:09:30Z
dc.date.available2023-09-26T23:09:30Z
dc.identifierRODRIGUES, A. B. F. et al. Hepatite granulomatosa em bovino causada por Mycobacterium avium subsp. paratuberculosis / Granulomatous hepatitis in cattle caused by Mycobacterium avium subsp. paratuberculosis. Arquivo Brasileiro de Medicina Veterinária e Zootecnia, v. 62, n. 6, p. 1495-1498, dez. 2010.
dc.identifier0102-0935
dc.identifierhttps://www.arca.fiocruz.br/handle/icict/6050
dc.identifier.urihttps://repositorioslatinoamericanos.uchile.cl/handle/2250/8887489
dc.descriptionSamples from intestines, liver, and lymph nodes were collected from a dairy steer with clinical suspicion of paratuberculosis. The samples were processed for histologic examination with hematoxylin-eosin and Zihel-Neelsen (ZN) staining for the detection of acid-fast bacilli (AFB), and submitted to immunohistochemistry (IHC). Macroscopic changes were observed in the small intestines, with thickening and corrugation of the mucosa. The main microscopic changes were found in small intestines, lymph vessels in the mesentery, and mesenteric lymph nodes characterized by enteritis, lymphangiectasia, and lymphadenitis. Liver presented with granulomatous hepatitis, an uncommon histopathological feature for paratuberculosis. The clinical features associated with positive culture of Mycobacterium avium subsp. paratuberculosis and detection of AFB by ZN and IHC in the cytoplasm of macrophages (epithelioid) in the intestinal mucosa and submucosa, lymph nodes, and liver were important to confirm the diagnosis of paratuberculosis.
dc.formatapplication/pdf
dc.languagepor
dc.rightsopen access
dc.subjectBovino
dc.subjectParatuberculose
dc.subjectHepatite
dc.subjectHistopatologia
dc.subjectBovine
dc.subjectParatuberculosis
dc.subjectHepatitis
dc.subjectHistopathology
dc.subjectHepatite/patologia
dc.subjectMycobacterium/patogenicidade
dc.subjectParatuberculose
dc.subjectBovinos
dc.titleHepatite granulomatosa em bovino causada por Mycobacterium avium subsp. paratuberculosis / Granulomatous hepatitis in cattle caused by Mycobacterium avium subsp. paratuberculosis
dc.typeArticle


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