dc.creatorBrito, Gilberto N. O.
dc.date2015-03-20T13:56:48Z
dc.date2015-03-20T13:56:48Z
dc.date2009
dc.date.accessioned2023-09-26T23:07:04Z
dc.date.available2023-09-26T23:07:04Z
dc.identifierBRITO, Gilberto N. O. Exercise and cognitive function: a hypothesis for the association of type II diabetes mellitus and Alzheimer's disease from an evolutionary perspective. Diabetol. metab. syndr., São Paulo, v. 1, n. 7, 2009.
dc.identifier1758-5996
dc.identifierhttps://www.arca.fiocruz.br/handle/icict/9782
dc.identifier.urihttps://repositorioslatinoamericanos.uchile.cl/handle/2250/8887037
dc.descriptionThe association of type II diabetes mellitus (DM2) with Alzheimer's disease (AD) has received considerable attention in recent years. In the present paper, a hypothesis for this association from an evolutionary perspective, with emphasis on the close interplay between exercise and cognitive function, will be advanced in order to provide a biological rationale for the notion that the fundamental metabolic features of DM2 act in the brain over a protracted time span to induce the neuropathological characteristics of Alzheimer's disease thereby producing cognitive impairment. It is hoped that this hypothesis puts the association of DM2 and AD on firm conceptual grounds from a biological perspective and offers directions for further research.
dc.formatapplication/pdf
dc.languageeng
dc.publisherBioMed Central
dc.rightsopen access
dc.subjectDiabetes Mellitus Tipo 2
dc.subjectDoença de Alzheimer
dc.titleExercise and cognitive function: a hypothesis for the association of type II diabetes mellitus and Alzheimer's disease from an evolutionary perspective
dc.typeArticle


Este ítem pertenece a la siguiente institución