Sickle cell anemia: delayed diagnosis in Bahia, Brazil-a largely Afro-descendant population

dc.creatorZanette, Angela Maria Dias
dc.creatorGonçalves, Marilda de Souza
dc.creatorBahia, Regina Célia Santos
dc.creatorNogueira, Luciana Vasconcelos Araujo
dc.creatorArruda, Sérgio Marcos
dc.date2017-06-01T16:11:58Z
dc.date2017-06-01T16:11:58Z
dc.date2011
dc.date.accessioned2023-09-26T23:06:54Z
dc.date.available2023-09-26T23:06:54Z
dc.identifierZANETTE, A. M. D. et al. Sickle cell anemia: delayed diagnosis in Bahia, Brazil--a largely Afro-descendant population. Ethnicity & Disease, v. 21, n. 2, p. 243-247, 2011.
dc.identifier1049-510X
dc.identifierhttps://www.arca.fiocruz.br/handle/icict/19086
dc.identifier.urihttps://repositorioslatinoamericanos.uchile.cl/handle/2250/8887006
dc.descriptionHemoglobinopathies are the most common genetic disorders in the world and include sickle cell anemia (SCA), which is a public health problem in Brazil. Nevertheless, the disease is highly unknown among health professionals, and delayed diagnosis constitutes an important cause of concern for caretakers of SCA patients. The purpose of this study was to compare the clinical and laboratory history of SCA patients whose diagnosis was established during the first year of life to those of other SCA patients who had delayed SCA diagnosis. Demographic, clinical, and laboratory data were all reviewed from 99 steady-state SCA patients who were followed in a public hematology and hemotherapy clinic in Salvador, Brazil. The patients were aged $12 years and attended the outpatient unit at least once from November 2008 to June 2009. The data were analyzed in 2010. For all patients, the mean age (6 SD) at diagnosis was 12.7(6 12.1) years, ranging from 0 to 47 years. Mean age was higher in patients whose SCA diagnosis was established after age 5 (32.9 6 11.9 years, P5.005). Increased unconjugated bilirubin, stroke and splenic sequestration were more prevalent in patients who were diagnosed in the first year of life (P5.043, .024 and .026 respectively).
dc.formatapplication/pdf
dc.languageeng
dc.publisherInternational Society on Hypertension in Blacks
dc.rightsopen access
dc.subjectAnemia falciforme
dc.subjectDoença falciforme
dc.subjectHemoglobinopatia
dc.subjectDiagnóstico atrasado
dc.subjectSickle Cell Anemia
dc.subjectSickle Cell Disease
dc.subjectHemoglobinopathy
dc.subjectDelayed Diagnosis
dc.subjectAnemia falciforme
dc.subjectDoença falciforme
dc.subjectHemoglobinopatias
dc.subjectDiagnóstico tardio
dc.titleSickle cell anemia: delayed diagnosis in Bahia, Brazil-a largely Afro-descendant population
dc.typeArticle


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