Araçatuba virus: A vaccinialike virus associated with infection in humans and cattle

dc.contributorUniversidade Estadual Paulista (UNESP)
dc.creatorDe Souza Trindade, Giliane
dc.creatorDa Fonseca, Flávio Guimarães
dc.creatorMarques, João Trindade
dc.creatorNogueira, Maurício Lacerda
dc.creatorMendes, Luiz Claudio Nogueira
dc.creatorBorges, Alexandre Secorun
dc.creatorPeiró, Juliana Regina
dc.creatorPituco, Edviges Maristela
dc.creatorBonjardim, Cláudio Antônio
dc.creatorFerreira, Paulo César Peregrino
dc.creatorKroon, Erna Geessien
dc.date2014-05-27T11:20:36Z
dc.date2016-10-25T18:18:26Z
dc.date2014-05-27T11:20:36Z
dc.date2016-10-25T18:18:26Z
dc.date2003-02-01
dc.date.accessioned2017-04-06T01:04:58Z
dc.date.available2017-04-06T01:04:58Z
dc.identifierEmerging Infectious Diseases, v. 9, n. 2, p. 155-160, 2003.
dc.identifier1080-6040
dc.identifierhttp://hdl.handle.net/11449/67194
dc.identifierhttp://acervodigital.unesp.br/handle/11449/67194
dc.identifier2-s2.0-0344211874
dc.identifierhttp://wwwnc.cdc.gov/eid/article/9/2/02-0244_article.htm
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/888674
dc.descriptionWe describe a vaccinialike virus, Araçatuba virus, associated with a cowpoxlike outbreak in a dairy herd and a related case of human infection. Diagnosis was based on virus growth characteristics, electron microscopy, and molecular biology techniques. Molecular characterization of the virus was done by using polymerase chain reaction amplification, cloning, and DNA sequencing of conserved orthopoxvirus genes such as the vaccinia growth factor (VGF), thymidine kinase (TK), and hemagglutinin. We used VGF-homologous and TK gene nucleotide sequences to construct a phylogenetic tree for comparison with other poxviruses. Gene sequences showed 99% homology with vaccinia virus genes and were clustered together with the isolated virus in the phylogenetic tree. Araçatuba virus is very similar to Cantagalo virus, showing the same signature deletion in the gene. Araçatuba virus could be a novel vaccinialike virus or could represent the spread of Cantagalo virus.
dc.languageeng
dc.relationEmerging Infectious Diseases
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectanimal cell
dc.subjectAracatuba virus
dc.subjectcattle disease
dc.subjectcontrolled study
dc.subjectcowpox
dc.subjectDNA sequence
dc.subjectDNA virus
dc.subjectgene amplification
dc.subjectgene cluster
dc.subjectgene deletion
dc.subjectgene sequence
dc.subjectmolecular biology
dc.subjectmolecular cloning
dc.subjectnonhuman
dc.subjectnucleotide sequence
dc.subjectOrthopoxvirus
dc.subjectphylogeny
dc.subjectpolymerase chain reaction
dc.subjectsequence analysis
dc.subjectsequence homology
dc.subjectVaccinia virus
dc.subjectVero cell
dc.subjectvirogenesis
dc.subjectvirus gene
dc.subjectvirus identification
dc.subjectvirus infection
dc.subjectvirus isolation
dc.subjectAnimals
dc.subjectBase Sequence
dc.subjectCattle
dc.subjectCattle Diseases
dc.subjectCommunicable Diseases, Emerging
dc.subjectGenes, Viral
dc.subjectHumans
dc.subjectMicroscopy, Electron
dc.subjectMolecular Sequence Data
dc.subjectPhylogeny
dc.subjectSequence Alignment
dc.subjectVaccinia
dc.subjectViral Proteins
dc.subjectViral Structural Proteins
dc.subjectViremia
dc.titleAraçatuba virus: A vaccinialike virus associated with infection in humans and cattle
dc.typeOtro


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