dc.creator | Santos, Rogério Lacerda dos | |
dc.creator | Lacerda, Maria Cláudia Mesquita | |
dc.creator | Gonçalves, Renato Torres | |
dc.creator | Martins, Marco Aurélio | |
dc.creator | Souza, Margareth Maria Gomes de | |
dc.date | 2018-11-29T15:55:50Z | |
dc.date | 2018-11-29T15:55:50Z | |
dc.date | 2012 | |
dc.date.accessioned | 2023-09-26T23:02:47Z | |
dc.date.available | 2023-09-26T23:02:47Z | |
dc.identifier | SANTOS, Rogério Lacerda dos; et al. Immunosuppressants: Implications in Orthodontics. Dental Press J. Orthod., v.17, n.2, p.55-61, 2012. | |
dc.identifier | 2176-9451 | |
dc.identifier | https://www.arca.fiocruz.br/handle/icict/30340 | |
dc.identifier | 2177-6709 | |
dc.identifier.uri | https://repositorioslatinoamericanos.uchile.cl/handle/2250/8886212 | |
dc.description | There are medications capable of affecting bone metabolism and the rate of tooth movement.
Among these medications are the immunosuppressants, which act by repressing the action of T lymphocytes, however
they can cause bone loss and consequently lead to osteoporosis. Osteoporosis is a common complication following
kidney, heart, liver or lung transplantation. The immunosuppressant treatment for preventing organ rejection
after transplantation, in general, includes glucocorticoids, cyclosporine, tacrolimus, and sirolimus. All these
drugs can have jeopardizing effects on bone mineral homeostasis and consequently influence tooth movement. In
recent years, however, the increasing use of immunosuppressants has raised questions about their effects on bone
metabolism in patients undergoing orthodontic treatment. | |
dc.format | application/pdf | |
dc.language | eng | |
dc.publisher | Dental Press Editora | |
dc.rights | open access | |
dc.subject | Ossos | |
dc.subject | Técnicas de Movimentação Dentária | |
dc.subject | Imunossupressor | |
dc.subject | Ortodontia | |
dc.subject | Immunosuppressant | |
dc.subject | Tooth movement | |
dc.subject | Bone | |
dc.subject | Orthodontics | |
dc.title | Immunosuppressants: Implications in Orthodontics | |
dc.type | Article | |