dc.creatorBhowmick, Tushar Suvra
dc.creatorDas, Mayukh
dc.creatorRuppitsch, Werner
dc.creatorStoeger, Anna
dc.creatorPietzka, Tatjana
dc.creatorAllerberger, Franz
dc.creatorRodrigues, Dália P.
dc.creatorSarker, B. L.
dc.date2019-01-17T10:17:18Z
dc.date2019-01-17T10:17:18Z
dc.date2009
dc.date.accessioned2023-09-26T23:01:24Z
dc.date.available2023-09-26T23:01:24Z
dc.identifierBHOWMICK, Tushar Suvra; et al. Detection of virulence-associated and regulatory protein genes in association with phage typing of human Vibrio cholerae from several geographical regions of the world. Journal of Medical Microbiology, v.58, p.1160–1167, 2009.
dc.identifier0022-2615
dc.identifierhttps://www.arca.fiocruz.br/handle/icict/31087
dc.identifier10.1099/jmm.0.008466-0
dc.identifier1473-5644
dc.identifier.urihttps://repositorioslatinoamericanos.uchile.cl/handle/2250/8885949
dc.descriptionVibrio cholerae O1, O139 and occasionally non-O1/non-O139 serogroups are most often responsible for epidemic and pandemic cholera. This study used genotypic patterns of PCRbased detection of virulence-associated and regulatory protein genes, along with phage typing, to characterize 86 V. cholerae strains. Thirty-eight of 53 O1 biotype El Tor strains harboured both tcpA classical and tcpA El Tor genes, and three El Tor strains lacked the V. cholerae O1-specific gene (Vc-O1); three O139 strains contained both Vc-O1 and Vc-O139 genes and seven out of ten non-O1/non-O139 strains possessed the Vc-O1 gene. The latter strains all harboured the virulence-associated genes ctxA, zot, ace, RS1, hlyA, ompU, rtxA and sxt. Two phage types, T27 and T25, were predominant in strains from different geographical regions of India, whereas more variation in phage susceptibility was observed for tetracycline-resistant strains from Kolkata. These results suggest that the pattern and distribution of virulence genes and phage types of V. cholerae are equally useful and discriminatory in tracing the origin of newly emerging strains.
dc.description2030-01-01
dc.formatapplication/pdf
dc.languageeng
dc.publisherMicrobiology Society
dc.rightsrestricted access
dc.subjectVibrio cholerae humano
dc.subjectvirulência
dc.subjectgenes de proteínas
dc.subjecttipagem fágica
dc.subjectHuman Vibrio cholerae
dc.subjectvirulence
dc.subjectregulatory protein genes
dc.subjectphage typing
dc.titleDetection of virulence-associated and regulatory protein genes in association with phage typing of human Vibrio cholerae from several geographical regions of the world
dc.typeArticle


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