Callitrichine gammaherpesvirus 3 and Human alphaherpesvirus 1 in New World Primate negative for yellow fever virus in Rio de Janeiro, Brazil

dc.creatorBonfim, Flávia Freitas de Oliveira
dc.creatorMares-Guia, Maria Angélica Monteiro de Mello
dc.creatorHorta, Marco Aurélio
dc.creatorChame, Marcia
dc.creatorLopes, Amanda de Oliveira
dc.creatorSantos, Rafael
dc.creatorMatias, Carlos Alexandre Rey
dc.creatorPinto, Marcelo Alves
dc.creatorFilippis, Ana Maria Bispo de
dc.creatorPaula, Vanessa Salete de
dc.date2022-05-01T13:47:34Z
dc.date2022-05-01T13:47:34Z
dc.date2022
dc.date.accessioned2023-09-26T23:00:02Z
dc.date.available2023-09-26T23:00:02Z
dc.identifierBONFIM, Flávia Freitas de Oliveira et al. Callitrichine gammaherpesvirus 3 and Human alphaherpesvirus 1 in New World Primate negative for yellow fever virus in Rio de Janeiro, Brazil. Memórias do Instituto Oswaldo Cruz, Rio de Janeiro, v. 117, e210258, p. 1-9, 2022.
dc.identifier0074-0206
dc.identifierhttps://www.arca.fiocruz.br/handle/icict/52491
dc.identifier10.1590/0074-02760210258
dc.identifier1678-8060
dc.identifier.urihttps://repositorioslatinoamericanos.uchile.cl/handle/2250/8885701
dc.descriptionCAPES, FAPERJ, FIOCRUZ/MS. The Flavivirus Laboratory was supported by CVSRL/FIOCRUZ, FAPERJ (grant no. E-26/2002.930/2016), The International Development Research Centre (IDRC) Canada (grant 108411-001).
dc.descriptionBACKGROUND: Herpesvirus transmission between humans and non-human primate (NHP) can occur through contact scratches with lesions, infected saliva, and mainly through contaminated food. Therefore, cross-infection can lead to severe illness or even death for both the animal and human. In 2017, during the yellow fever (YF) outbreak in Brazil, species of the New World Primates (NWP) from Rio de Janeiro state, tested negative for yellow fever virus (YFV) detection. OBJECTIVES: To evaluate herpesvirus in the population NWP in Rio de Janeiro. METHODS: To investigate, liver samples of 283 NWP, from several regions of the state of Rio de Janeiro, were tested for the herpesvirus family using a Pan-polymerase chain reaction (Pan-PCR) and sequencing. FINDINGS: 34.6% (98/283) tested positive for at least one herpesvirus; 29.3% (83/283) tested positive to Human alphaherpesvirus 1 (HSV-1), this virus from humans can be lethal to New World monkey; 13% (37/283) were detected Callitrichine gammaherpesvirus 3 (CalHV-3), responsible for lymphoproliferative disease that can be fatal in NWP. In addition, CalHV-3 / HSV-1 co-infection was in 11.6% (33/283) of the samples. MAIN CONCLUSIONS: Pan-herpesvirus was useful to identify species-specific herpesviruses and virus from human that can infect animals. Furthermore, during an outbreak of YF other infections should be monitored.
dc.formatapplication/pdf
dc.languagepor
dc.publisherFiocruz/IOC
dc.rightsopen access
dc.subjectCallitrichine gammaherpesvirus 3
dc.subjectHuman alphaherpesvirus 1
dc.subjectNon-human primates
dc.titleCallitrichine gammaherpesvirus 3 and Human alphaherpesvirus 1 in New World Primate negative for yellow fever virus in Rio de Janeiro, Brazil
dc.typeArticle


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