| dc.creator | Lima, Pedro Antônio Schmidt do Prado | |
| dc.creator | Costa-Ferro, Zaquer Suzana Munhoz | |
| dc.creator | Souza, Bruno Solano de Freitas | |
| dc.creator | Cruz, Ivana Beatrice Manica da | |
| dc.date | 2021-12-08T16:50:17Z | |
| dc.date | 2021-12-08T16:50:17Z | |
| dc.date | 2021 | |
| dc.date.accessioned | 2023-09-26T22:52:32Z | |
| dc.date.available | 2023-09-26T22:52:32Z | |
| dc.identifier | LIMA, Pedro Antônio Schmidt do Prado et al. Is there a place for cellular therapy in depression? World Journal of Psychiatry, v. 11, n. 9, p. 553-567, 2021. | |
| dc.identifier | 2220-3206 | |
| dc.identifier | https://www.arca.fiocruz.br/handle/icict/50215 | |
| dc.identifier | 10.5498/wjp.v11.i9.553 | |
| dc.identifier.uri | https://repositorioslatinoamericanos.uchile.cl/handle/2250/8884245 | |
| dc.description | Conselho Nacional
de Desenvolvimento Cientifico -
CNPq. | |
| dc.description | Although efforts have been made to improve the pharmacological treatment of
depression, approximately one-third of patients with depression do not respond
to conventional therapy using antidepressants. Other potential non-pharmacological
therapies have been studied in the last years, including the use of
mesenchymal stem cell therapies to treat depression. These therapies are reviewed
here since it is clinically relevant to develop innovative therapeutics to treat
psychiatric patients. Experimental data corroborate that mesenchymal stem cell
therapy could be considered a potential treatment for depression based on its antiinflammatory
and neurotrophic properties. However, some clinical trials
involving treatment of depression with stem cells are in progress, but with no
published results. These studies and other future clinical investigations will be
crucial to define how much mesenchymal stem cells can effectively be used in
psychiatric clinics as a strategy for supporting depression treatment. | |
| dc.format | application/pdf | |
| dc.language | eng | |
| dc.publisher | Baishideng Publishing Group | |
| dc.rights | open access | |
| dc.subject | Transtornos de Humor | |
| dc.subject | Transplante de células-tronco | |
| dc.subject | Transplante de células-tronco mesenquimais | |
| dc.subject | Inflamação | |
| dc.subject | Imunomodulação | |
| dc.subject | Depressão | |
| dc.subject | Mood disorders | |
| dc.subject | Stem cells transplant | |
| dc.subject | Mesenchymal stem-cells transplant | |
| dc.subject | Inflammation | |
| dc.subject | Immunomodulation | |
| dc.subject | Depression | |
| dc.title | Is there a place for cellular therapy in depression? | |
| dc.type | Article | |
