dc.contributorUniversidade Estadual Paulista (UNESP)
dc.creatorChahine, Jorge
dc.creatorNymeyer, Hugh
dc.creatorLeite, Vitor Barbanti Pereira
dc.creatorSocci, Nicholas D.
dc.creatorOnuchic, José Nelson
dc.date2014-05-27T11:20:27Z
dc.date2016-10-25T18:17:46Z
dc.date2014-05-27T11:20:27Z
dc.date2016-10-25T18:17:46Z
dc.date2002-04-22
dc.date.accessioned2017-04-06T01:02:24Z
dc.date.available2017-04-06T01:02:24Z
dc.identifierPhysical Review Letters, v. 88, n. 16, p. 1681011-1681014, 2002.
dc.identifier0031-9007
dc.identifierhttp://hdl.handle.net/11449/66875
dc.identifierhttp://acervodigital.unesp.br/handle/11449/66875
dc.identifier10.1103/PhysRevLett.88.168101
dc.identifierWOS:000174905400050
dc.identifier2-s2.0-19044396284.pdf
dc.identifier2-s2.0-19044396284
dc.identifierhttp://dx.doi.org/10.1103/PhysRevLett.88.168101
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/888388
dc.descriptionExperiments with fast folding proteins are beginning to address the relationship between collapse and folding. We investigate how different scenarios for folding can arise depending on whether the folding and collapse transitions are concurrent or whether a nonspecific collapse precedes folding. Many earlier studies have focused on the limit in which collapse is fast compared to the folding time; in this work we focus on the opposite limit where, at the folding temperature, collapse and folding occur simultaneously. Real proteins exist in both of these limits. The folding mechanism varies substantially in these two regimes. In the regime of concurrent folding and collapse, nonspecific collapse now occurs at a temperature below the folding temperature (but slightly above the glass transition temperature).
dc.languageeng
dc.relationPhysical Review Letters
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectComputer simulation
dc.subjectCrystal lattices
dc.subjectEnergy transfer
dc.subjectFluorescence
dc.subjectGlass transition
dc.subjectResonance
dc.subjectThermal effects
dc.subjectX ray scattering
dc.subjectFolding funnels
dc.subjectProteins
dc.titleSpecific and nonspecific collapse in protein folding funnels
dc.typeOtro


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