SARS-CoV-2 Molecular Epidemiology Can Be Enhanced by Occupational Health: The Experience of Monitoring Variants of Concern in Workplaces in Rio de Janeiro, Brazil

dc.creatorKuriyama, Sergio N.
dc.creatorFarjun, Bruna
dc.creatorHenriques-Santos, Bianca Monteiro
dc.creatorCabanelas, Adriana
dc.creatorAbrantes, Juliana Lourenço
dc.creatorGesto, João
dc.creatorFidalgo Neto, Antonio A.
dc.creatorSouza, Thiago Moreno L.
dc.date2022-07-04T12:17:13Z
dc.date2022-07-04T12:17:13Z
dc.date2022
dc.date.accessioned2023-09-26T22:49:37Z
dc.date.available2023-09-26T22:49:37Z
dc.identifierKURIYAMA, Sergio N. et al. SARS-CoV-2 Molecular Epidemiology Can Be Enhanced by Occupational Health: The Experience of Monitoring Variants of Concern in Workplaces in Rio de Janeiro, Brazil. Frontiers in Medicine, v.9, Article 862284, p. 1 - 7, Apr. 2022.
dc.identifier2298-858X
dc.identifierhttps://www.arca.fiocruz.br/handle/icict/53623
dc.identifier10.3389/fmed.2022.862284
dc.identifier.urihttps://repositorioslatinoamericanos.uchile.cl/handle/2250/8883667
dc.descriptionThe emergence of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has led to extra caution in workplaces to avoid the coronavirus disease 2019 (COVID-19). In the occupational environment, SARS-CoV-2 testing is a powerful approach in providing valuable information to detect, monitor, and mitigate the spread of the virus and preserve productivity. Here a centralized Occupational Health Center providedmolecular diagnosis and genomic sequences for companies and industries in Rio de Janeiro, Brazil. From May to August 2021, around 20% of the SARS-CoV-2 positive nasopharyngeal swabs from routinely tested workers were sequenced and reproduced the replacement of Gamma with Delta variant observed in regular surveillance programs. Moreover, as a proof-of-concept on the sensibility of the occupational health genomic surveillance program described here, it was also found: i) the primo-identification of B.1.139 and A.2.5 viral genomes in Brazil and ii) an improved dating of Delta VoC evolution, by identifying earlier cases associated with AY-related genomes. We interpret that SARS- CoV-2 molecular testing of workers, independent of symptom presentation, provides an earlier opportunity to identify variants. Thus, considering the continuous monitoring of SARS-CoV-2 in workplaces, positive samples from occupation health programs should be regarded as essential to improve the knowledge on virus genetic diversity and VoC emergence.
dc.formatapplication/pdf
dc.languageeng
dc.publisherFrontiers Media
dc.rightsopen access
dc.subjectCOVID-19
dc.subjectSARS-CoV-2
dc.subjectAssistência médica ocupacional
dc.subjectVigilância
dc.subjectVariantes de preocupação (VOCs)
dc.subjectSequência molecular
dc.subjectSequenciamento (NGS) de próxima geração (profundo)
dc.subjectCOVID-19
dc.subjectSARS-CoV-2
dc.subjectOccupational medical care
dc.subjectSurveillance
dc.subjectVariants of concern (VOCs)
dc.subjectMolecular sequence
dc.subjectNext generation (deep) sequencing (NGS)
dc.titleSARS-CoV-2 Molecular Epidemiology Can Be Enhanced by Occupational Health: The Experience of Monitoring Variants of Concern in Workplaces in Rio de Janeiro, Brazil
dc.typeArticle


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