Comparative immunological recognition of proteins from New Guinea "C" dengue virus type 2 prototype and from a dengue virus type 2 strain isolated in the State of Rio de Janeiro, Brazil

dc.creatorCôrtes, Luzia M. de C.
dc.creatorBarth, Ortrud Monika
dc.creatorPantoja, Josery R.
dc.creatorAlves, Carlos R.
dc.date2020-11-13T18:31:01Z
dc.date2020-11-13T18:31:01Z
dc.date2003
dc.date.accessioned2023-09-26T22:47:30Z
dc.date.available2023-09-26T22:47:30Z
dc.identifierCÔRTES, Luzia M. de C. et al. Comparative immunological recognition of proteins from New Guinea "C" dengue virus type 2 prototype and from a dengue virus type 2 strain isolated in the State of Rio de Janeiro, Brazil. Memórias do Instituto Oswaldo Cruz, Rio de Janeiro, v. 98, n. 3, p. 331-334, Apr. 2003.
dc.identifier0074-0276
dc.identifierhttps://www.arca.fiocruz.br/handle/icict/44396
dc.identifier10.1590/S0074-02762003000300007
dc.identifier1678-8060
dc.identifier.urihttps://repositorioslatinoamericanos.uchile.cl/handle/2250/8883232
dc.descriptionThe protein profiles of the New Guinea “C” dengue virus type 2 (DENV-2)prototype and those of a Brazilian DENV-2 isolated in the State of Rio de Janeiro in 1995 were compared. SDS-PAGE analysis showed that the virus from Rio de Janeiro expresses NS5 (93.0 kDa), NS3 (66.8 kDa) E (62.4 kDa) and NS1 (41.2 kDa) proteins differently from the New Guinea “C” virus. The immunoblot revealed specificity and antigenicity for the NS3 protein from DENV-2 Rio de Janeiro mainly in primary infections, convalescent cases, and in secondary infections in both cases and only antigenicity for E and NS1 proteins for both viruses in primary and secondary infections.
dc.formatapplication/pdf
dc.languageeng
dc.publisherFundação Oswaldo Cruz. Instituto Oswaldo Cruz.
dc.rightsopen access
dc.subjectFlavivírus
dc.subjectProteínas Dengue vírus tipo 2
dc.subjectAntigenicidade
dc.subjectBrasil
dc.subjectRio de Janeiro
dc.subjectFlavivirus
dc.subjectDengue virus type 2 proteins
dc.subjectAntigenicity
dc.subjectRio de Janeiro
dc.subjectBrazil
dc.titleComparative immunological recognition of proteins from New Guinea "C" dengue virus type 2 prototype and from a dengue virus type 2 strain isolated in the State of Rio de Janeiro, Brazil
dc.typeArticle


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