Apoptosis of non-parasitized red blood cells in malaria: a putative mechanism involved in the pathogenesis of anaemia

dc.creatorTotino, Paulo R. R.
dc.creatorMagalhães, Aline D.
dc.creatorSilva, Luciene A.
dc.creatorBanic, Dalma M.
dc.creatorDaniel-Ribeiro, Cláudio Tadeu
dc.creatorCruz, Maria de Fátima Ferreira da
dc.date2018-04-19T16:36:11Z
dc.date2018-04-19T16:36:11Z
dc.date2010
dc.date.accessioned2023-09-26T22:45:53Z
dc.date.available2023-09-26T22:45:53Z
dc.identifierTOTINO, Paulo Renato R. et al. Apoptosis of non-parasitized red blood cells in malaria: a putative mechanism involved in the pathogenesis of anaemia. Malaria Journal, v.9:150, 5p, 2010.
dc.identifier1475-2875
dc.identifierhttps://www.arca.fiocruz.br/handle/icict/25962
dc.identifier10.1186/1475-2875-9-350
dc.identifier.urihttps://repositorioslatinoamericanos.uchile.cl/handle/2250/8882909
dc.descriptionSevere anaemia is a common complication of Plasmodium falciparum malaria in hyperendemic regions. Premature elimination of non-parasitized red blood cells (nRBC) has been considered as one mechanism involved in the genesis of severe malaria anaemia. It has been reported that apoptosis can occur in RBC and, consequently, this cell death process could contribute to anaemia. This study was performed to evaluate the susceptibility of nRBC to apoptosis in a malaria anaemia murine model.
dc.formatapplication/pdf
dc.languageeng
dc.publisherBioMed Central
dc.rightsopen access
dc.subjectMalária
dc.subjectAnemia
dc.subjectPlasmodium falciparum
dc.subjectMalaria
dc.subjectAnaemia
dc.subjectPlasmodium falciparum
dc.titleApoptosis of non-parasitized red blood cells in malaria: a putative mechanism involved in the pathogenesis of anaemia
dc.typeArticle


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