Health-related quality of life assessment among people living with HIV in Rio de Janeiro, Brazil: a cross-sectional study

dc.creatorCastro, Rodolfo
dc.creatorDe Boni, Raquel Brandini
dc.creatorLuz, Paula Mendes
dc.creatorVelasque, Luciane
dc.creatorLopes, Livia V.
dc.creatorMedina-Lara, Antonieta
dc.creatorCardoso, Sandra W.
dc.creatorOliveira, Marilia S.
dc.creatorFriedman, Ruth K.
dc.creatorGrinsztejn, Beatriz
dc.creatorSantos, Valdiléa Gonçalves Veloso dos
dc.date2018-12-07T13:15:14Z
dc.date2018-12-07T13:15:14Z
dc.date2018
dc.date.accessioned2023-09-26T22:43:58Z
dc.date.available2023-09-26T22:43:58Z
dc.identifierCASTRO, Rodolfo et al. Health-related quality of life assessment among people living with HIV in Rio de Janeiro, Brazil: a cross-sectional study. Quality of Life Research, p. 1-11, Nov. 2018.
dc.identifier0962-9343
dc.identifierhttps://www.arca.fiocruz.br/handle/icict/30418
dc.identifier10.1007/s11136-018-2044-8
dc.identifier.urihttps://repositorioslatinoamericanos.uchile.cl/handle/2250/8882507
dc.descriptionPurpose To assess health-related quality of life (HRQoL) and its associated factors among people living with HIV/AIDS (PLWHA) in Rio de Janeiro, Brazil. Methods A cross-sectional study including PLWHA receiving usual HIV-care at Instituto Nacional de Infectologia Evandro Chagas (INI/Fiocruz) was conducted between 2014 and 2016 in Rio de Janeiro, Brazil. The EQ-5D-3L assessed HRQoL; PHQ-2 and ASSIST were used for screening depression and substance use, respectively. Clinical variables were obtained from the INI/Fiocruz cohort database, and structured questions evaluated intimate partner violence, sexual abstinence and relationship status. Data were analysed using multivariable Tobit regression model. Results A total of 1480 PLWHA were included: 64.7% were male at birth (38.4% men who have sex with men [MSM], 24.3% heterosexual men and 2% transgender women [TGW]); median age was 43.1 years, and 95.8% were receiving antiretroviral therapy. The median EQ-5D-3L utility score was 0.801. Results showed that the following factors: MSM and women; older age; lower educational level; no engagement in a relationship; depression screening positive; polysubstance use; and, detectable viral load were independently associated with worse HRQoL. Conclusions PLWHA under care at INI/Fiocruz presented good HRQoL. Polysubstance use, depression and lower educational level were among the factors negatively associated with HRQoL. This was the first time that the EQ-5D-3L utility scores were calculated for a considerable number of PLWHA in Brazil, which is a fundamental piece of information for future cost-effectiveness analysis.
dc.description2038-08-30
dc.formatapplication/pdf
dc.languageeng
dc.publisherSpringer
dc.rightsrestricted access
dc.subjectAge factors
dc.subjectDepression
dc.subjectEducational status
dc.subjectGender
dc.subjectQuality of life
dc.subjectSubstance abuse
dc.subjectViral load
dc.subjectHIV
dc.titleHealth-related quality of life assessment among people living with HIV in Rio de Janeiro, Brazil: a cross-sectional study
dc.typeArticle


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