Th1/Th2 cytokine profile in patients coinfected with HIV and Leishmania in Brazil.

dc.creatorRodrigues, Maria Zilma Andrade
dc.creatorGrassi, Maria Fernanda Rios
dc.creatorMehta, Sanjay
dc.creatorZhang, Xing-Quan
dc.creatorGois, Luana Leandro
dc.creatorSchooley, Robert T
dc.creatorBadaró, Roberto José da Silva
dc.date2014-10-06T12:19:11Z
dc.date2014-10-06T12:19:11Z
dc.date2011
dc.date.accessioned2023-09-26T22:43:17Z
dc.date.available2023-09-26T22:43:17Z
dc.identifierRODRIGUES, M. Z. et al. Th1/Th2 cytokine profile in patients coinfected with HIV and Leishmania in Brazil. Clinical Vaccine Immunology, v. 18, n. 10, p. 1765-1769, 2011.
dc.identifier1556-679X
dc.identifierhttps://www.arca.fiocruz.br/handle/icict/8507
dc.identifier10.1128/CVI.00076-11
dc.identifier.urihttps://repositorioslatinoamericanos.uchile.cl/handle/2250/8882361
dc.descriptionTo evaluate the effects of HIV on immune responses in cutaneous leishmaniasis (CL), we quantified cytokine levels from plasma and stimulated peripheral blood mononuclear cells (PBMCs) from individuals infected with HIV and/or CL. Gamma interferon (IFN- ) and interleukin 13 (IL-13) levels and the ratio of IFN- to IL-10 produced in response to stimulation with soluble Leishmania antigens were significantly lower in HIV-Leishmania-coinfected patients than in CL-monoinfected patients.
dc.formatapplication/pdf
dc.languageeng
dc.publisherAmerican Society for Microbiology
dc.rightsopen access
dc.subjectCitocinas/sangue
dc.subjectInfecções por HIV/complicações
dc.subjectInfecções por HIV/imunologia
dc.subjectLeishmaniose Cutânea/complicações
dc.subjectLeishmaniose Cutânea/imunologia
dc.subjectCélulas Th1/imunologia
dc.subjectCélulas Th2/imunologia
dc.subjectBrasil
dc.subjectCélulas Cultivadas
dc.subjectCitocinas/secreção
dc.subjectHumanos
dc.subjectLeucócitos Mononucleares/imunologia
dc.subjectPlasma/química
dc.titleTh1/Th2 cytokine profile in patients coinfected with HIV and Leishmania in Brazil.
dc.typeArticle


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