Infective dermatitis associated with human T-cell lymphotropic virus type 1: evaluation of 42 cases observed in Bahia, Brazil

dc.creatorOliveira, Maria de Fátima Santos Paim de
dc.creatorFatal, Priscila Lima
dc.creatorPrimo, Janeusa Rita Leite
dc.creatorSilva, José Lucas Sena da
dc.creatorBatista, Everton da Silva
dc.creatorVallve, Maria de Lourdes Farre
dc.creatorBittencourt, Achilea Candida Lisboa
dc.date2015-06-10T18:16:59Z
dc.date2015-06-10T18:16:59Z
dc.date2012
dc.date.accessioned2023-09-26T22:40:19Z
dc.date.available2023-09-26T22:40:19Z
dc.identifierOLIVEIRA, Maria de Fátima Santos Paim de et al. Infective dermatitis associated with human T-cell lymphotropic virus type 1: evaluation of 42 cases observed in Bahia, Brazil. Clinical of Infectious Diseases, v. 54, n. 12, p. 1714-1719, June 2012.
dc.identifier1058-4838
dc.identifierhttps://www.arca.fiocruz.br/handle/icict/10782
dc.identifier10.1093/cid/cis273
dc.identifier1537-6591
dc.identifier.urihttps://repositorioslatinoamericanos.uchile.cl/handle/2250/8881743
dc.descriptionBackground. Infective dermatitis associated with human T-cell lymphotropic virus type 1 (HTLV-1; IDH) is a chronic recurrent eczema affecting HTLV-1–infected children. The epidemiological and dermatological characteristics of IDH are described, and their principal diagnostic criteria are reevaluated. Methods. Forty-two patients were included: 40 patients serologically positive for HTLV-1 and 2 seronegative patients who tested positive in polymerase chain reaction (PCR) assays. Results. The mean age at onset of the disease was 2.6 ± 2.4 years (range, 2 months–11 years). The mean duration of breast-feeding was 24.2 months. The lesions were erythematous, scaly, and crusted, always affecting the scalp and retroauricular regions. Crusting of the nostrils was observed in 64.3% of the patients. Of the 36 patients followed up, 23 had the active disease. The age at which IDH disappeared in the others was 10–20 years. Conclusions. The onset of IDH may occur earlier than reported in the literature. The scalp and retroauricular regions are always affected, and lesions are invariably present in ≥3 areas. Crusting of the nostrils cannot be considered an obligatory factor for the diagnosis of IDH. The recurring nature of IDH was a characteristic found in all cases. Patients with classic IDH lesions who are serologically negative should be investigated by PCR. Therefore, the indispensable criteria for diagnosis are (1) presence of erythematous-scaly, exudative, and crusted lesions involving ≥3 areas, including the scalp and retroauricular regions; (2) recurring nature of the lesions; and (3) a finding of HTLV-1 infection by serology or molecular biology.
dc.formatapplication/pdf
dc.languageeng
dc.publisherOxford University Press
dc.rightsopen access
dc.subjectPolymerase chain reaction
dc.subjectDermatitis
dc.subjectBrazil
dc.subjectBreast feeding
dc.subjectChild
dc.subjectHuman T-lymphotropic virus 1
dc.subjectScalp
dc.subjectInfections
dc.subjectDiagnosis
dc.subjectNaris
dc.subjectSymptom onset
dc.subjectEczema/epidemiologia
dc.subjectInfecções por HTLV-I/complicações
dc.subjectVírus 1 Linfotrópico T Humano/isolamento & purificação
dc.subjectDermatopatias Infecciosas/epidemiologia
dc.subjectAdolescente
dc.subjectBrasil/epidemiologia
dc.subjectCriança
dc.subjectPré-Escolar
dc.subjectTécnicas de Laboratório Clínico/métodos
dc.subjectEczema/diagnóstico
dc.subjectFeminino
dc.subjectInfecções por HTLV-I/virologia
dc.subjectHumanos
dc.subjectLactente
dc.subjectMasculino
dc.subjectPescoço/patologia
dc.subjectNariz/patologia
dc.subjectReação em Cadeia da Polimerase/métodos
dc.subjectRecidiva
dc.subjectCouro Cabeludo/patologia
dc.subjectDermatopatias Infecciosas/diagnóstico
dc.titleInfective dermatitis associated with human T-cell lymphotropic virus type 1: evaluation of 42 cases observed in Bahia, Brazil
dc.typeArticle


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