Detection of Hepatitis C Virus RNA in Saliva Is Not Related to Oral Health Status or Viral Load

dc.creatorLins, Liliane
dc.creatorAlmeida, Herbert
dc.creatorVitvitski, Ludmila
dc.creatorCarmo, Theomira Mauadie de Azevedo
dc.creatorParaná, Raymundo
dc.creatorReis, Mitermayer Galvão dos
dc.date2011-07-28T18:27:28Z
dc.date2011-07-28T18:27:28Z
dc.date2005
dc.date.accessioned2023-09-26T22:38:34Z
dc.date.available2023-09-26T22:38:34Z
dc.identifierLINS, L. et al. Detection of hepatitis C virus RNA in saliva is not related to oral health status or viral load. Journal of Medical Virology, v. 77, n. 2, p. 216-220, 2005.
dc.identifier0146-6615
dc.identifierhttps://www.arca.fiocruz.br/handle/icict/2785
dc.identifier10.1002/jmv.20438
dc.identifier.urihttps://repositorioslatinoamericanos.uchile.cl/handle/2250/8881393
dc.descriptionHepatitis C is a worldwide public health problem and its transmission is clearly associated with the parenteral route, however, the virus has also been isolated from other body fluids. Hepatitis C virus (HCV) RNA has been detected in saliva, yet the relationship between HCV and oral pathology is not clearly understood. Therefore, an investigation on HCV-RNA in saliva and its correlation with oral pathology was undertaken. Saliva and blood samples were collected from 50 anti-HCV positive patients and from 25 patients with non-HCV chronic liver disease. HCV-RNA was detected in all of the saliva samples from the HCV positive group. None of the saliva or serum samples from the non-HCV group were positive for HCV-RNA. The patients were examined for dental and oral health (dentate, partially dentate, edentulous, evidence of gum disease, or mucosal lesions); however, no correlation was found between HCV-RNA in saliva, oral health, and viral load. These results suggest that HCV-RNA presence in saliva is independent of the viral load and the oral pathology of HCV positive individuals
dc.formatapplication/pdf
dc.languageeng
dc.rightsopen access
dc.subjectHepacivirus
dc.subjectRNA Viral
dc.subjectSaliva
dc.subjectAnticorpos Anti-Hepatite
dc.subjectGenes Virais
dc.subjectCarga Viral
dc.subjectHepacivirus
dc.subjectRNA Viral
dc.subjectSaliva
dc.subjectAnticorpos Anti-Hepatite
dc.titleDetection of Hepatitis C Virus RNA in Saliva Is Not Related to Oral Health Status or Viral Load
dc.typeArticle


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