CD4(+)CD25(High) Treg cells in HIV/HTLV co-infected patients with neuropathy: high expression of Alpha4 integrin and lower expression of Foxp3 transcription factor

dc.creatorMatavele Chissumba, Raquel
dc.creatorBarbosa, Suse Dayse Silva
dc.creatorAugusto, Ângelo
dc.creatorMaueia, Cremildo
dc.creatorMabunda, Nédio
dc.creatorGudo Jr., Eduardo Samo
dc.creatorBhatt, Nilesh
dc.creatorJani, Ilesh
dc.creatorSavino, Wilson
dc.date2019-07-04T15:14:12Z
dc.date2019-07-04T15:14:12Z
dc.date2015
dc.date.accessioned2023-09-26T22:37:40Z
dc.date.available2023-09-26T22:37:40Z
dc.identifierCHISSUMBA, Raquel Matavele et al. CD4+CD25High Treg cells in HIV/HTLV Co-infected patients with neuropathy: high expression of Alpha4 integrin and lower expression of Foxp3 transcription factor. BMC Immunology, v. 16, n. 52, p. 1-9, 2015.
dc.identifier1471-2172
dc.identifierhttps://www.arca.fiocruz.br/handle/icict/33841
dc.identifier10.1186/s12865-015-0116-x
dc.identifier.urihttps://repositorioslatinoamericanos.uchile.cl/handle/2250/8881196
dc.descriptionRegulatory CD4 T cells (Tregs) are critical in maintaining the homeostasis of the immune system. Quantitative or phenotypic alterations and functional impairment of Tregs have been associated with the development of pathologies including those of the central nervous system. Individuals with HIV-1/HTLV-1 co-infection are more prone to develop neurological complications. The aim of this study was to characterize phenotypically Treg cells in HIV-1/HTLV-1 co-infected Mozambican individuals presenting neurological symptoms.
dc.formatapplication/pdf
dc.languageeng
dc.publisherBMC
dc.rightsopen access
dc.subjectHIV
dc.subjectCD4+CD25High Treg cells
dc.subjectHTLV
dc.subjectNeuropatia
dc.subjectFator de transcrição Foxp3
dc.subjectHIV
dc.subjectNeuropathy
dc.subjectCD4 + CD25Células Tregs
dc.subjectHTLV
dc.subjectFoxp3 transcription factor
dc.titleCD4(+)CD25(High) Treg cells in HIV/HTLV co-infected patients with neuropathy: high expression of Alpha4 integrin and lower expression of Foxp3 transcription factor
dc.typeArticle


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