The moderation of multimorbidity and depressive symptoms on cognition

dc.creatorAraújo, Jacyra Azevedo Paiva de
dc.creatorXavier, Érika Fialho Morais
dc.creatorRodrigues, Elisângela da Silva
dc.creatorMachado, Daiane Borges
dc.creatorBarreto, Marcos E.
dc.creatorKanaan, Richard A.
dc.creatorBarreto, Mauricio L.
dc.creatorAraújo, Luís Fernando Silva Castro de
dc.date2022-12-16T12:20:11Z
dc.date2022-12-16T12:20:11Z
dc.date2022
dc.date.accessioned2023-09-26T22:36:50Z
dc.date.available2023-09-26T22:36:50Z
dc.identifierARAÚJO, Jacyra Azevedo Paiva de et al. The moderation of multimorbidity and depressive symptoms on cognition. Brazilian Journal of Psychiatry, v. 44, n. 6, p. 1-13, 2022.
dc.identifier1809-452X
dc.identifierhttps://www.arca.fiocruz.br/handle/icict/55994
dc.identifier10.47626/1516-4446-2022-2601
dc.identifier.urihttps://repositorioslatinoamericanos.uchile.cl/handle/2250/8881021
dc.descriptionUK Biotechnology and Biological Sciences Research Council. UK Medical Research Council and the University of Cambridg. U.S. National Institute of Mental Health. UK Medical Research Council.
dc.descriptionOBJECTIVE: Multimorbidity, or the occurrence of two or more chronic conditions, is a global challenge, with implications for mortality, morbidity, disability, and life quality. Psychiatric disorders are common among the chronic diseases that affect patients with multimorbidity. It is still not well understood whether psychiatric symptoms, especially depressive symptoms, moderate the effect of multimorbidity on cognition. METHODS: We used a large (n=2,681) dataset to assess whether depressive symptomatology moderates the effect of multimorbidity on cognition using structural equation modelling. RESULTS: It was found that the more depressive symptoms and chronic conditions, the worse the cognitive performance, and the higher the educational level, the better the cognitive performance. We found a significant but weak (0.009; p = 0.04) moderating effect. CONCLUSION: We have provided the first estimate of the moderating effect of depression on the relation between multimorbidity and cognition, which was small. Although this moderation has been implied by many previous studies, it was never previously estimated.
dc.formatapplication/pdf
dc.languageeng
dc.publisherAssociação Brasileira de Psiquiatria
dc.rightsopen access
dc.subjectMultimorbidade
dc.subjectEpidemiologia
dc.subjectEnvelhecimento
dc.subjectModelagem de equações estruturais
dc.subjectMultimorbidity
dc.subjectEpidemiology
dc.subjectAging
dc.subjectStructural equation modeling
dc.subjectMultimorbidade
dc.subjectEpidemiologia
dc.subjectEnvelhecimento
dc.subjectAnálise de Classes Latentes
dc.titleThe moderation of multimorbidity and depressive symptoms on cognition
dc.typeArticle


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