Grandisin caused morphological changes larval and toxicity on Aedes aegypti

dc.creatorLeite, Ana Carolina C. F.
dc.creatorKato, Massuo J.
dc.creatorSoares, Renata O. A.
dc.creatorGuimarães, Anthony E.
dc.creatorSantos-Mallet, Jacenir R.
dc.creatorCabral, Marise M. O.
dc.date2017-05-09T15:11:06Z
dc.date2017-05-09T15:11:06Z
dc.date2012
dc.date.accessioned2023-09-26T22:34:33Z
dc.date.available2023-09-26T22:34:33Z
dc.identifierLEITE, Ana Carolina C. F. et al. Grandisin caused morphological changes larval and toxicity on Aedes aegypti. Revista Brasileira de Farmacognosia, v.22, n.3, p.517-521, May / June 2012.
dc.identifier0102-695X
dc.identifierhttps://www.arca.fiocruz.br/handle/icict/18793
dc.identifier10.1590/S0100-695X20125000016
dc.identifier.urihttps://repositorioslatinoamericanos.uchile.cl/handle/2250/8880597
dc.descriptionDengue is a tropical disease caused by an arbovirus transmitted by Aedes aegypti. Since no effective vaccine is available for treating dengue, the present study focused on population vector control through investigating the use of the lignan grandisin, isolated from Piper solmsianum C. DC., Piperaceae, against the larvae of A. aegypti. Grandisin caused larval (L3) mortality at LC50 150 μg/mL. Histological analysis on A. aegypti larvae treated with grandisin (LC50 50 μg/mL) showed changes in the anterior-middle midgut, with intense tissue destruction and cell disorganization.
dc.formatapplication/pdf
dc.languageeng
dc.publisherSociedade Brasileira de Farmacognosia
dc.rightsopen access
dc.subjectAedes aegypti
dc.subjectDengue
dc.subjectControle de vetor de população
dc.subjectGrandisin
dc.subjectAedes aegypti
dc.subjectDengue
dc.subjectpopulation vector control
dc.subjectGrandisin
dc.titleGrandisin caused morphological changes larval and toxicity on Aedes aegypti
dc.typeArticle


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