Association between skin parasitism and a granulomatous inflammatory pattern in canine visceral leishmaniosis

dc.creatordosSantos, Washington Luis Conrado
dc.creatorDavid, John R.
dc.creatorBadaró, Roberto José da Silva
dc.creatorFreitas, Luiz Antonio Rodrigues de
dc.date2014-07-08T13:52:18Z
dc.date2014-07-08T13:52:18Z
dc.date2004
dc.date.accessioned2023-09-26T22:32:35Z
dc.date.available2023-09-26T22:32:35Z
dc.identifierSANTOS, Washington Luis Conrado dos et al. Association between skin parasitism and a granulomatous inflammatory pattern in canine visceral leishmaniosis. Parasitology, Research, v. 92, n. 2, p. 89-94, 2004.
dc.identifier0932-0113
dc.identifierhttps://www.arca.fiocruz.br/handle/icict/7879
dc.identifier10.1007/s00436-003-1016-1
dc.identifier.urihttps://repositorioslatinoamericanos.uchile.cl/handle/2250/8880545
dc.descriptionIn this work we examined 76 stray dogs from an area of endemic visceral leishmaniosis, in order to determine whether the presence of skin inflammation or a specific inflammatory pattern could be taken as indicative of infection with Leishmania chagasi, and whether the parasite burden in the skin could be associated with the intensity or the nature of the inflammatory process. Inflammatory infiltrates were observed in the skin of 51 out of 55 animals with diagnosis of leishmaniosis, and in 17 out of 21 animals without signs of infection. Amastigotes were identified in the skin of 29 out of the 55 animals with diagnosis of leishmaniosis. Granuloma and a monomorphic macrophage inflammatory infiltrate, and not a mixed focal or mixed diffuse inflammation, were significantly associated with skin parasitism, both in terms of frequency ( P=0.015 in the Chi-square test) and intensity ( P=0.005 in the Kruskal-Wallis test). A low parasite burden was associated with a multifocal inflammatory pattern.
dc.formatapplication/pdf
dc.languageeng
dc.publisherSpringer Verlag
dc.rightsopen access
dc.subjectDoenças do Cão/fisiopatologia
dc.subjectGranuloma/fisiopatologia
dc.subjectInflamação/fisiopatologia
dc.subjectLeishmania/patogenicidade
dc.subjectLeishmaniose Visceral/veterinária
dc.subjectPele/parasitologia
dc.subjectAnimais
dc.subjectDoenças do Cão/parasitologia
dc.subjectCães
dc.subjectGranuloma/parasitologia
dc.subjectInflamação/parasitologia
dc.subjectLeishmaniose Visceral/parasitologia
dc.subjectLeishmaniose Visceral/fisiopatologia
dc.titleAssociation between skin parasitism and a granulomatous inflammatory pattern in canine visceral leishmaniosis
dc.typeArticle


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