Immunodetection of toxins in historesin-embedded sections of Phoneutria nigriventer venom glands using laser confocal scanning microscopy

dc.creatorSilva, Luciana Maria
dc.creatorPimenta, Rafael Nacif
dc.creatorOrtolani, Paula Ladeira
dc.creatorMoura, Layla Mosqueira
dc.creatorCordeiro, Marta do Nascimento
dc.creatorChavez-Olórtegui, Carlos
dc.creatorPimenta, Paulo Filemon Paolucci
dc.creatorFortes-Dias, Consuelo Latorre
dc.date2019-10-04T18:34:30Z
dc.date2019-10-04T18:34:30Z
dc.date2019
dc.date.accessioned2023-09-26T22:32:06Z
dc.date.available2023-09-26T22:32:06Z
dc.identifierSILVA, Luciana Maria et al. Immunodetection of toxins in historesin-embedded sections of Phoneutria nigriventer venom glands using laser confocal scanning microscopy. Toxicon, v. 167, p. 168-171, 2019.
dc.identifier0041-0101
dc.identifierhttps://www.arca.fiocruz.br/handle/icict/36201
dc.identifier10.1016/j.toxicon.2019.06.018
dc.identifier.urihttps://repositorioslatinoamericanos.uchile.cl/handle/2250/8880445
dc.descriptionIn the last decades, main advances were achieved in the identification, structural and pharmacological characterization of Phoneutria nigriventer toxins. However, studies on the venom-producing apparatus are rare. Presently, we applied immunolabeling to historesin-embedded cross-sections of P. nigriventer venom glands. Toxins and toxin-secreting cells were successfully located in situ, using laser confocal scanning microscopy. The methodological strategy was successful and may be applied in future studies on venom glands and other secreting tissues, in general.
dc.description2022-01-01
dc.formatapplication/pdf
dc.languageeng
dc.publisherElsevier Ltd
dc.rightsrestricted access
dc.subjectArmed spider
dc.subjectPhoneutria nigriventer
dc.subjectToxin immunodetection
dc.subjectVenom gland
dc.subjectVenom toxin secretion
dc.titleImmunodetection of toxins in historesin-embedded sections of Phoneutria nigriventer venom glands using laser confocal scanning microscopy
dc.typeArticle


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