First report of a blaNDM-resistant gene in a Klebsiella aerogenes clinical isolate from Brazil

dc.creatorSoares CRP
dc.creatorOliveira-Júnior JB
dc.creatorFirmo EF.
dc.date2023-03-31T15:28:54Z
dc.date2023-03-31T15:28:54Z
dc.date2020
dc.date.accessioned2023-09-26T22:27:22Z
dc.date.available2023-09-26T22:27:22Z
dc.identifierSoares CRP, Oliveira-Júnior JB, Firmo EF. First report of a blaNDM-resistant gene in a Klebsiella aerogenes clinical isolate from Brazil. Rev Soc Bras Med Trop. 2020.
dc.identifier0037-8682
dc.identifierhttps://www.arca.fiocruz.br/handle/icict/57643
dc.identifier10.1590/0037-8682-0262-2020
dc.identifier.urihttps://repositorioslatinoamericanos.uchile.cl/handle/2250/8879452
dc.descriptionCarbapenemase-resistant enterobacteria that produce the blaNDM gene are found worldwide. However, this is the first report of blaNDM in Klebsiella aerogenes in Brazil. Methods: The identification of bacterial species was performed using anautomated system and confirmed by biochemical tests, 16S rRNA gene sequencing, and detection of resistance genes. Results: The clinical isolate showed minimum inhibitory concentration resistance to meropenem and polymyxin B at 8mg/L and 4mg/L, respectively. Only the blaNDM gene was detected. Conclusions: The current report of the bla NDM gene in isolated MDR enterobacteria indicates that this gene can spread silently in a hospital setting.
dc.formatapplication/pdf
dc.languageeng
dc.rightsrestricted access
dc.subjectKlebsiella aerogenes
dc.subjectblaNDM gene
dc.subjectmetallo-betalactamase
dc.subjectCarbapenemase
dc.subjectMultidrug-resistant
dc.titleFirst report of a blaNDM-resistant gene in a Klebsiella aerogenes clinical isolate from Brazil
dc.typeArticle


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