Trypanosoma cruzi activates mouse cardiac fibroblasts in vitro leading to fibroblast-myofibroblast transition and increase in expression of extracellular matrix proteins

dc.creatorCoelho, Laura Lacerda
dc.creatorPereira, Isabela Resende
dc.creatorPereira, Mirian Claudia de Souza
dc.creatorMesquita, Liliane
dc.creatorLannes-Vieira, Joseli
dc.creatorAdesse, Daniel
dc.creatorGarzoni, Luciana Ribeiro
dc.date2018-10-04T11:31:41Z
dc.date2018-10-04T11:31:41Z
dc.date2018
dc.date.accessioned2023-09-26T22:27:20Z
dc.date.available2023-09-26T22:27:20Z
dc.identifierCOELHO, Laura Lacerda; et al. Trypanosoma cruzi activates mouse cardiac fibroblasts in vitro leading to fibroblastmyofibroblast transition and increase in expression of extracellular matrix proteins. Parasites & Vectors, v.11, n.72, 11p, 2018.
dc.identifier1756-3305
dc.identifierhttps://www.arca.fiocruz.br/handle/icict/29313
dc.identifier10.1186/s13071-018-2614-1
dc.identifier.urihttps://repositorioslatinoamericanos.uchile.cl/handle/2250/8879443
dc.descriptionCardiac fibrosis is a consequence of chronic chagasic cardiomyopathy (CCC). In other cardiovascular diseases, the protagonist role of fibroblasts in cardiac fibrosis is well established. However, the role of cardiac fibroblasts (CFs) in fibrosis during the CCC is not clear. Here, our aim was to investigate the effect of Trypanosoma cruzi, the etiological agent of Chagas disease on CFs activation.
dc.formatapplication/pdf
dc.languageeng
dc.publisherBioMed Central
dc.rightsopen access
dc.subjectDoença de Chagas
dc.subjectTrypanosoma cruzi
dc.subjectFibrose
dc.subjectMatriz Extracelular
dc.subjectFibroblastos cardíacos
dc.subjectChagas disesase
dc.subjectTrypanosoma cruzi
dc.subjectFibrosis
dc.subjectCardiac fibroblasts
dc.subjectExtracellular matrix
dc.titleTrypanosoma cruzi activates mouse cardiac fibroblasts in vitro leading to fibroblast-myofibroblast transition and increase in expression of extracellular matrix proteins
dc.typeArticle


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