The effect of changing the mode of ventilation on the arterial-to-end-tidal CO2 difference and physiological dead space in laterally and dorsally recumbent horses during halothane anesthesia

dc.contributorUniversidade Estadual Paulista (UNESP)
dc.creatorTeixeira Neto, Francisco José
dc.creatorLuna, Stélio Pacca Loureiro
dc.creatorMassone, Flavio
dc.creatorThomassian, Armen
dc.creatorVargas, José L. R.
dc.creatorJunior, José R. S.
dc.creatorD'Utra Vaz, Beatriz B.
dc.creatorCrocci, Adalberto José
dc.date2014-05-27T11:19:59Z
dc.date2016-10-25T18:16:42Z
dc.date2014-05-27T11:19:59Z
dc.date2016-10-25T18:16:42Z
dc.date2000-12-01
dc.date.accessioned2017-04-06T00:58:15Z
dc.date.available2017-04-06T00:58:15Z
dc.identifierVeterinary Surgery, v. 29, n. 2, p. 200-205, 2000.
dc.identifier0161-3499
dc.identifierhttp://hdl.handle.net/11449/66344
dc.identifierhttp://acervodigital.unesp.br/handle/11449/66344
dc.identifier10.1111/j.1532-950X.2000.00200.x
dc.identifierWOS:000085694300009
dc.identifier2-s2.0-0034149870
dc.identifier0000-0001-5312-9076
dc.identifierhttp://dx.doi.org/10.1111/j.1532-950X.2000.00200.x
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/887927
dc.descriptionObjective - To evaluate the effect of changing the mode of ventilation from spontaneous to controlled on the arterial-to-end-tidal CO2 difference [P(a-ET)CO2] and physiological dead space (VD(phys)/VT) in laterally and dorsally recumbent halothane-anesthetized horses. Study Design - Prospective, experimental, nonrandomized trial. Animals - Seven mixed breed adult horses (1 male and 6 female) weighing 320 ± 11 kg. Methods - Horses were anesthetized in 2 positions - right lateral and dorsal recumbency - with a minimum interval of 1 month. Anesthesia was maintained with halothane in oxygen for 180 minutes. Spontaneous ventilation (SV) was used for 90 minutes followed by 90 minutes of controlled ventilation (CV). The same ventilator settings were used for both laterally and dorsally recumbent horses. Arterial blood gas analysis was performed every 30 minutes during anesthesia. End-tidal CO2 (PETCO2) was measured continuously. P(a-ET)CO2 and VD(phys)/VT were calculated. Statistical analysis included analysis of variance for repeated measures over time, followed by Student-Newman-Keuls test. Comparison between groups was performed using a paired t test; P < .05 was considered significant. Results - P(a-ET)CO2 and VD(phys)/VT increased during SV, whereas CV reduced these variables. The variables did not change significantly throughout mechanical ventilation in either group. Dorsally recumbent horses showed greater P(a-ET)CO2 and VD(phys)/VT values throughout. PaCO2 was greater during CV in dorsally positioned horses. Conclusions and Clinical Relevance - Changing the mode of ventilation from spontaneous to controlled was effective in reducing P(a-ET)CO2 and physiological dead space in both laterally and dorsally recumbent halothane-anesthetized horses. Dorsal recumbency resulted in greater impairment of effective ventilation. Capnometry has a limited value for accurate estimation of PaCO, in anesthetized horses, although it may be used to evaluate pulmonary function when paired with arterial blood gas analysis. © Copyright 2000 by The American College of Veterinary Surgeons.
dc.languageeng
dc.relationVeterinary Surgery
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjecthalothane
dc.subjectinhalation anesthetic agent
dc.subjectanimal
dc.subjectanimal disease
dc.subjectartificial ventilation
dc.subjectbody posture
dc.subjectfemale
dc.subjecthorse
dc.subjectlung dead space
dc.subjectmale
dc.subjectphysiology
dc.subjectprospective study
dc.subjectAnesthetics, Inhalation
dc.subjectAnimals
dc.subjectFemale
dc.subjectHalothane
dc.subjectHorses
dc.subjectMale
dc.subjectPosture
dc.subjectProspective Studies
dc.subjectRespiration, Artificial
dc.subjectRespiratory Dead Space
dc.titleThe effect of changing the mode of ventilation on the arterial-to-end-tidal CO2 difference and physiological dead space in laterally and dorsally recumbent horses during halothane anesthesia
dc.typeOtro


Este ítem pertenece a la siguiente institución