Increased risk of allergic rhinitis among children delivered by cesarean section: a cross-sectional study nested in a birth cohort

dc.creatorBrandão, Heli Vieira
dc.creatorVieira, Graciete Oliveira
dc.creatorVieira, Tatiana de Oliveira
dc.creatorCamargos, Paulo Augusto
dc.creatorTeles, Carlos Antonio de Souza
dc.creatorGuimarães, Armênio Costa
dc.creatorCruz, Alvaro Augusto
dc.creatorCruz, Constança Margarida Sampaio
dc.date2017-04-07T16:54:36Z
dc.date2017-04-07T16:54:36Z
dc.date2016
dc.date.accessioned2023-09-26T22:21:09Z
dc.date.available2023-09-26T22:21:09Z
dc.identifierBRANDÃO, H. V. et al. Increased risk of allergic rhinitis among children delivered by cesarean section: a cross-sectional study nested in a birth cohort. BMC Pediatrics, v. 16, p. 57, 2016.
dc.identifier1471-2431
dc.identifierhttps://www.arca.fiocruz.br/handle/icict/18315
dc.identifier10.1186/s12887-016-0594-x
dc.identifier.urihttps://repositorioslatinoamericanos.uchile.cl/handle/2250/8878223
dc.descriptionCarlos Antônio de Souza Teles. Fundação Oswaldo Cruz. Instituto Gonçalo Moniz. Salvador, BA, Brasil. “Documento produzido em parceria ou por autor vinculado à Fiocruz, mas não consta à informação no documento”.
dc.descriptionResearch Support Foundation of the State of Bahia (FAPESB)
dc.descriptionFew studies have evaluated the association between delivery by cesarean section (CS) and asthma, allergic rhinitis and chronic rhinitis and whether this association is different in children with and without a family history of asthma. This study aims to investigate whether children born by CS have a higher chance to develop asthma, allergic rhinitis and chronic rhinitis and to evaluate the influence of parental history of asthma on these associations. Methods: This is a cross-sectional study of 672 children nested in a birth cohort evaluated at 6-years of age. Asthma and chronic/allergic rhinitis were identified by means of the mother’s responses to the ISAAC questionnaire. The association between CS, asthma, chronic rhinitis and allergic rhinitis was evaluated by multivariable logistic regression. The evidence of effect modification of parental history of asthma on the association CS and outcomes was examined by introducing interactions terms in the logistic regression models adjusting for confounders. Results: Asthma was not associated with birth by CS irrespective of parental history of asthma (odds ratio (OR) 1.03; 95 % CI 0.61–1.74). Chronic rhinitis and allergic rhinitis were both significantly associated with birth by CS but only in the subgroup of children with by parental history of asthma (OR 1.56; 95 % CI 1.04–2.34) and (OR 1.60; 95 % CI 1.01–2.55) respectively, after adjustment for confounders. The parental history of asthma was a effect modifier in the association between CS, chronic rhinitis and allergic rhinitis (p for effect modification = 0.10 and 0.02, respectively). Conclusion: CS increases the risk of chronic rhinitis and allergic rhinitis in children at 6 years of age with parental history of asthma. Health professionals must be alerted with regard to the increased risk of allergic rhinitis and made aware this is another reason to avoid unnecessary CS.
dc.formatapplication/pdf
dc.languageeng
dc.publisherBioMed Central
dc.rightsopen access
dc.subjectAsma
dc.subjectRinite alérgica
dc.subjectCesárea
dc.subjectCrianças
dc.subjectAsthma
dc.subjectAllergic rhinitis
dc.subjectCesarean
dc.subjectChildren
dc.titleIncreased risk of allergic rhinitis among children delivered by cesarean section: a cross-sectional study nested in a birth cohort
dc.typeArticle


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