Cohort study on canine emigration and Leishmania infection in an endemic area for American visceral leishmaniasis. Implications for the disease control.

dc.creatorSilva, Moacir Paranhos
dc.creatorNascimento, Eliane Góes
dc.creatorMelro, M. C. B. F
dc.creatorOliveira, Geraldo Gileno de Sá
dc.creatordosSantos, Washington Luis Conrado
dc.creatorPontes-de-Carvalho, Lain Carlos
dc.creatorSantos, A. J. Oliveira dos
dc.date2014-05-28T18:23:22Z
dc.date2014-05-28T18:23:22Z
dc.date1998
dc.date.accessioned2023-09-26T22:19:27Z
dc.date.available2023-09-26T22:19:27Z
dc.identifierSILVA, M. P. et al. Cohort study on canine emigration and Leishmania infection in an endemic area for American visceral leishmaniasis. Implications for the disease control. Acta Tropica, v. 69, n. 1, p. 75–83, 1998.
dc.identifier0001-706X
dc.identifierPII S0001-706X(97)00116-2
dc.identifierhttps://www.arca.fiocruz.br/handle/icict/7664
dc.identifier.urihttps://repositorioslatinoamericanos.uchile.cl/handle/2250/8877848
dc.descriptionAmerican visceral leishmaniasis is a main public health matter in Brazil. Since dogs have been incriminated as the main urban reservoir of AVL agent Leishmania chagasi, a cohort study aimed at understanding the dynamics of the canine infection was carried out in Jequie´—an endemic community in the Northeast of Brazil. The inhabited urban and periurban areas of Jequie´ were divided into 140 clusters of 0.25 km2. All 1681 dogs domiciled in 34 randomly selected clusters were screened for Leishmania antibodies in an enzyme-linked immunosorbent assay. After the seropositive dogs were painlessly eliminated, a cohort of 1286 seronegative dogs was followed up for 18 months, yielding a total of 1739.7 dog-years. The overall incidence of Leishmania infection, as assessed by the detection of Leishmania antibodies in blood samples collected every six months, was 6.55 cases:100 dog-years (95% confidence interval; CI 6.04–7.26). Two subsets of clusters, with 0.70 and 1.35 relative risks of infection, were identified. The annual emigration rate was 2.26 cases:100 dog-years (95% CI 1.86–2.66). The implications of these findings for the control of American visceral leishmaniasis are discussed.
dc.formatapplication/pdf
dc.languageeng
dc.publisherElsevier Science B.V
dc.rightsopen access
dc.subjectDoenças do Cão/epidemiologia
dc.subjectLeishmaniose/veterinária
dc.subjectAnimais
dc.subjectAnticorpos Antiprotozoários/sangue
dc.subjectBrasil/epidemiologia
dc.subjectReservatórios de Doenças
dc.subjectDoenças do Cão/imunologia
dc.subjectDoenças do Cão/parasitologia
dc.subjectCães
dc.subjectEnsaio de Imunoadsorção Enzimática
dc.subjectFeminino
dc.subjectIncidência
dc.subjectLeishmaniose/epidemiologia
dc.subjectLeishmaniose/imunologia
dc.subjectLeishmaniose/parasitologia
dc.subjectMasculino
dc.titleCohort study on canine emigration and Leishmania infection in an endemic area for American visceral leishmaniasis. Implications for the disease control.
dc.typeArticle


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