dc.creatorTorres, Rosália Morais
dc.creatorCorreia, Dalmo
dc.creatorNunes, Maria do Carmo Pereira
dc.creatorDutra, Walderez O.
dc.creatorTalvani, André
dc.creatorSousa, Andréa Silvestre
dc.creatorMendes, Fernanda de Souza Nogueira Sardinha
dc.creatorScanavaccax, Maurício Ibrahim
dc.creatorIbrahim, Maurício
dc.creatorMoreira, Maria da Consolação Vieira
dc.creatorSouza, Dilma do Socorro Moraes de
dc.creatorOliveira Junior, Wilson de
dc.creatorMartins, Silvia Marinho
dc.creatorDias, João Carlos Pinto
dc.date2021-12-21T23:33:00Z
dc.date2021-12-21T23:33:00Z
dc.date2021
dc.date.accessioned2023-09-26T22:17:07Z
dc.date.available2023-09-26T22:17:07Z
dc.identifierTORRES, Rosália Moraes et al. Prognosis of chronic Chagas heart disease and other pending clinical challenges. Memórias do Instituto Oswaldo Cruz, Rio de Janeiro, v. 116, p. 1-17, 2021.
dc.identifier0074-0276
dc.identifierhttps://www.arca.fiocruz.br/handle/icict/50513
dc.identifier10.1590/0074-02760210172
dc.identifier.urihttps://repositorioslatinoamericanos.uchile.cl/handle/2250/8877312
dc.descriptionIn this chapter, the main prognostic markers of Chagas heart disease are addressed, with an emphasis on the most recent findings and questions, establishing the basis for a broad discussion of recommendations and new approaches to managing Chagas cardiopathy. The main biological and genetic markers and the contribution of the electrocardiogram, echocardiogram and cardiac magnetic resonance are presented. We also discuss the most recent therapeutic proposals for heart failure, thromboembolism and arrhythmias, as well as current experience in heart transplantation in patients suffering from severe Chagas cardiomyopathy. The clinical and epidemiological challenges introduced by acute Chagas disease due to oral contamination are discussed. In addition, we highlight the importance of ageing and comorbidities in influencing the outcome of chronic Chagas heart disease. Finally, we discuss the importance of public policies, the vital role of funding agencies, universities, the scientific community and health professionals, and the application of new technologies in finding solutions for better management of Chagas heart disease.
dc.formatapplication/pdf
dc.languageeng
dc.publisherInstituto Oswaldo Cruz
dc.rightsopen access
dc.subjectChagas disease
dc.subjectChagas cardiomyopathy
dc.subjectPrognosis
dc.subjectEvolution markers
dc.subjectPublic health
dc.titlePrognosis of chronic Chagas heart disease and other pending clinical challenges
dc.typeArticle


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