dc.creatorPascarella, Stefano
dc.creatorBianchi, Martina
dc.creatorGiovanetti, Marta
dc.creatorNarzi, Daniele
dc.creatorCauda, Roberto
dc.creatorCassone, Antonio
dc.creatorCiccozzi, Massimo
dc.date2022-12-23T14:39:11Z
dc.date2022-12-23T14:39:11Z
dc.date2022
dc.date.accessioned2023-09-26T22:15:09Z
dc.date.available2023-09-26T22:15:09Z
dc.identifierPASCARELLA, Stefano et al. The SARS‐CoV‐2 Mu variant should not be left aside: It warrants attention for its immuno-escaping ability. Journal of Medical Virology, v. 94, p. 2479-2486, 2022.
dc.identifier1096-9071
dc.identifierhttps://www.arca.fiocruz.br/handle/icict/56188
dc.identifier10.1002/jmv.27663
dc.identifier.urihttps://repositorioslatinoamericanos.uchile.cl/handle/2250/8876862
dc.descriptionThe COVID‐19 pandemic continues to have a threatening impact on a global scale, largely due to the emergence of newly SARS‐CoV‐2 variants. The Mu (PANGO lineage B.1.621), was first identified in Colombia in January 2021 and was classified as a variant of interest (VOI) in August 2021, due to a constellation of mutations that likely‐mediate an unexpectedly enhanced immune resistance to inactivated vaccineelicited antibodies. Despite recent studies suggesting that the Mu variant appears to have less infectivity than the Delta variant, here we examined the structural effect of the Mu spike protein mutations and predicted the potential impact on infectivity of the Mu variant compared with the Delta and Delta plus spike protein.
dc.formatapplication/pdf
dc.languageeng
dc.publisherWiley
dc.rightsopen access
dc.subjectVariação antigênica
dc.subjectSARS coronavírus
dc.subjectBioestatística e Bioinformática
dc.subjectGenética
dc.subjectClassificação de vírus
dc.subjectAntigenic variation
dc.subjectBiostatistics & Bioinformatics
dc.subjectGenetics
dc.subjectSARS coronavirus
dc.subjectVirus classification
dc.titleThe SARS‐CoV‐2Mu variant should not be left aside: It warrants attention for its immuno‐escaping ability
dc.typeArticle


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