Endocrine disruptors, estrogenic activity by the YES bioassay, and acute toxicity in Southeastern Brazil metropolitan surface waters

dc.creatorNascimento, Marilia Teresa Lima do
dc.creatorSantos, Ana Dalva de Oliveira
dc.creatorCunha, Danieli Lima da
dc.creatorFelix, Louise Cruz
dc.creatorGomes, Giselle
dc.creatorRangel, Carlos Marclei Arruda
dc.creatorHauser-Davis, Rachel Ann
dc.creatorFonseca, Estefan Monteiro da
dc.creatorBila, Daniele Maia
dc.creatorBaptista Neto, José Antônio
dc.date2022-07-21T18:41:27Z
dc.date2022-07-21T18:41:27Z
dc.date2022
dc.date.accessioned2023-09-26T22:13:14Z
dc.date.available2023-09-26T22:13:14Z
dc.identifierNASCIMENTO, Maria Teresa Lima do et al. Endocrine disruptors, estrogenic activity by the YES bioassay, and acute toxicity in Southeastern Brazil metropolitan surface waters. Geochimíca Brasiliensis, v. 36, e-22005, p. 1 - 14, 2022.
dc.identifier2358-2812
dc.identifierhttps://www.arca.fiocruz.br/handle/icict/53906
dc.identifier10.21715/GB2358-2812.202236005
dc.identifier.urihttps://repositorioslatinoamericanos.uchile.cl/handle/2250/8876432
dc.descriptionThis study aimed to determine endocrine disruptors in urbanized rivers Maracanã and Mangue Channel in Rio de Janeiro the second most populated city in Brazil. Bisphenol A, 17β-estradiol, estriol, and 17α-ethinylestradiol were determined by high-performance liquid chromatography with a diode array detector and fluorescence detector In addition, the evaluation of estrogenic activity was performed by the YES bioassay (Yeast estrogen screen) with the Saccharomyces cerevisiae yeast, and acute toxicity assays were performed using Daphnia similis and Vibrio fischeri. Estrogenic activity in the water samples ranged from below the limit of detection (<LD) to 1.6 ng L-1, while bisphenol A ranged from 22.3 to 1325.2 ng L-1 and estrogens 17β- estradiol from <LD to 55.2 ng L-1, estriol from <LD to 313.7 ng L-1 and 17α- ethinylestradiol, from <LD to 409.4 ng L-1. The acute toxicity was not detected in both analyzed organisms. The present study indicates a serious level of pollution by the compounds evaluated with significant risks to the aquatic ecosystem, mainly for Guanabara Bay which receives urbanized river discharge. Therefore, recommending the need for systematic monitoring and mitigating actions in these water bodies.
dc.formatapplication/pdf
dc.languageeng
dc.publisherSociedade Brasileira de Geoquímica
dc.rightsopen access
dc.subjectAtividade estrogênica
dc.subjectDesreguladores endócrinos
dc.subjectBioensaio YES
dc.subjectEnsaios de toxicidade
dc.subjectEstrogenic activity
dc.subjectEndocrine disrupters
dc.subjectYES bioassay
dc.subjectToxicity assays
dc.titleEndocrine disruptors, estrogenic activity by the YES bioassay, and acute toxicity in Southeastern Brazil metropolitan surface waters
dc.typeArticle


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