Intralesional treatment with meglumine antimoniate in three patients with New World cutaneous leishmaniasis and large periarticular lesions with comorbidities

dc.creatorPimentel, Maria Inês Fernandes
dc.creatorVasconcellos, Érica de Camargo Ferreira E.
dc.creatorRibeiro, Carla de Oliveira
dc.creatorLyra, Marcelo Rosandiski
dc.creatorSaheki, Mauricio Naoto
dc.creatorSalgueiro, Mariza de Matos
dc.creatorAntonio, Liliane de Fátima
dc.creatorSchubach, Armando de Oliveira
dc.date2019-01-21T14:01:37Z
dc.date2019-01-21T14:01:37Z
dc.date2017
dc.date.accessioned2023-09-26T22:10:24Z
dc.date.available2023-09-26T22:10:24Z
dc.identifierPIMENTEL, Maria Inês Fernandes et al. Intralesional treatment with meglumine antimoniate in three patients with New World cutaneous leishmaniasis and large periarticular lesions with comorbidities. Revista da Sociedade Brasileira de Medicina Tropical, v. 50, n. 2, p. 269-272, Mar./Apr. 2017.
dc.identifier0037-8682
dc.identifierhttps://www.arca.fiocruz.br/handle/icict/31179
dc.identifier10.1590/0037-8682-0323-2016
dc.identifier1678-9849
dc.identifier.urihttps://repositorioslatinoamericanos.uchile.cl/handle/2250/8875758
dc.descriptionAlthough New World cutaneous leishmaniasis is not itself a life-threatening disease, its treatment with systemic antimonials can cause toxicity that can be dangerous to some patients. Intralesional meglumine antimoniate provides a viable, less toxic alternative. Herein, we describe an alternative treatment with subcutaneous intralesional injections of meglumine antimoniate into large periarticular lesions of three patients with cutaneous leishmaniasis and comorbidities. This treatment was safe, successful, and well tolerated. This case series suggests that intralesional meglumine antimoniate is an effective therapy for cutaneous leishmaniasis, even with periarticular lesions. This hypothesis should be tested in controlled clinical trials.
dc.formatapplication/pdf
dc.languageeng
dc.publisherSociedade Brasileira de Medicina Tropical
dc.rightsopen access
dc.subjectCutaneous leishmaniasis
dc.subjectMeglumine antimoniate
dc.subjectIntralesional injections
dc.titleIntralesional treatment with meglumine antimoniate in three patients with New World cutaneous leishmaniasis and large periarticular lesions with comorbidities
dc.typeArticle


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