| dc.creator | Pires, Renata Cássia | |
| dc.creator | Boité, Mariana C | |
| dc.creator | D'Andrea, Paulo S. | |
| dc.creator | Herrera, Heitor M | |
| dc.creator | Cupolillo, Elisa | |
| dc.creator | Jansen, Ana Maria | |
| dc.creator | Roque, André Luiz R | |
| dc.date | 2015-06-08T14:01:52Z | |
| dc.date | 2015-06-08T14:01:52Z | |
| dc.date | 2014 | |
| dc.date.accessioned | 2023-09-26T22:09:55Z | |
| dc.date.available | 2023-09-26T22:09:55Z | |
| dc.identifier | PIRES, Renata Cássia et al. Distinct Leishmania Species Infecting Wild Caviomorph Rodents (Rodentia: Hystricognathi) from Brazil. PLOS Neglected Tropical Diseases, v.8, n.12, 8p, 2014. | |
| dc.identifier | https://www.arca.fiocruz.br/handle/icict/10700 | |
| dc.identifier | 10.1371/journal.pntd.0003389 | |
| dc.identifier.uri | https://repositorioslatinoamericanos.uchile.cl/handle/2250/8875643 | |
| dc.description | Leishmaniasis is a major public health problem expanding
in Brazil and one of the reasons is that we still have poor
knowledge of some aspects of the biology and epidemiology
of Leishmania species, including the role of wild
mammals. Caviomorph rodents, some of the oldest
Leishmania spp. hosts, are widely dispersed in Brazil and
reported as potential reservoirs of Leishmania parasites.
Spleen fragments of 373 brazilian caviomorph rodents
from 20 species were investigated for Leishmania infection.
The molecular algorithm proposed to diagnose the
infection associate the sensitivity of a molecular target
with multiple copies with the specificity of another marker
with discriminatory taxonomic ability between species.
These demonstrated their usefulness in identifying most of
the parasite species infecting the rodents, including the
description of species in previously unknown hosts and in
areas not previously included in their known distribution,
such as L. shawi in Thrichomys inermis from Northeastern
Brazil and L. naiffi in T. fosteri from Western Brazil. Although
the percent of infection by molecular diagnosis was 4.6%,
the serology demonstrated that about 51% of them had
been exposed to Leishmania parasites pointing that
caviomorph rodents are inserted in enzootic cycles of
Leishmania, to a higher extent than currently recognized. | |
| dc.format | application/pdf | |
| dc.language | eng | |
| dc.publisher | Plos One | |
| dc.rights | open access | |
| dc.subject | Brasil | |
| dc.subject | Leishmania | |
| dc.subject | Rodents | |
| dc.subject | Brazil | |
| dc.subject | Caviomorph Rodents | |
| dc.subject | Roedores | |
| dc.subject | Leishmania | |
| dc.title | Distinct Leishmania Species Infecting Wild Caviomorph Rodents (Rodentia: Hystricognathi) from Brazil | |
| dc.type | Article | |
