Trypanosoma cruzi strain-specific monoclonal antibodies: identification of Colombian strain flagellates in the insect vector

dc.creatorSimone, Salvatore Giovanni de
dc.creatorPontes-de-Carvalho, Lain Carlos
dc.creatorOliva, Otavio F. P
dc.creatorAndrade, Sonia Gumes
dc.creatorCastro Filho, Bernardo Galvão
dc.date2014-09-10T17:01:17Z
dc.date2014-09-10T17:01:17Z
dc.date1987
dc.date.accessioned2023-09-26T22:07:20Z
dc.date.available2023-09-26T22:07:20Z
dc.identifierSIMONE, S. G. et al. Trypanosoma cruzi strain-specific monoclonal antibodies: identification of Colombian strain flagellates in the insect vector. Transactions of the Royal Society of Tropical Medicine and Hygiene, v. 81, n. 5, p. 750-754, 1987.
dc.identifier0035-9203
dc.identifierhttps://www.arca.fiocruz.br/handle/icict/8343
dc.identifier.urihttps://repositorioslatinoamericanos.uchile.cl/handle/2250/8875037
dc.descriptionSpleen cells from mice immunized with insect-derived Typanosoma crUm metacyclic trypomastigotes were used to obtain Colombian strain-specific monoclonal antibodies. At least 4 different strain-specific antigens were recognized by the monoclonal antibodies on epimastigotes or metacyclic trypomastigotes. There was no reactivity with other stages of Colombian strain T. cruzi, nor with any stage of 15 other T. cruzi strains or isolates, nor with 22 other Trypanosomatidae. One of the monoclonal antibodies was used to identify, by indirect immunofluorescence, Colombian strain flagellates in cryostat sections or glass-slide smears of the insect vector’s intestine.
dc.formatapplication/pdf
dc.languageeng
dc.publisherRoyal Society of Tropical Medicine and Hygiene
dc.rightsopen access
dc.subjectAnticorpos Monoclonais/uso diagnóstico
dc.subjectAnticorpos Antiprotozoários/análise
dc.subjectTrypanosoma cruzi/imunologia
dc.subjectAnimais
dc.subjectAnticorpos Antiprotozoários/imunologia
dc.subjectImunofluorescência
dc.subjectInsetos Vetores/imunologia
dc.subjectInsetos Vetores/parasitologia
dc.subjectTriatominae/imunologia
dc.subjectTripanossomíase/parasitologia
dc.titleTrypanosoma cruzi strain-specific monoclonal antibodies: identification of Colombian strain flagellates in the insect vector
dc.typeArticle


Este ítem pertenece a la siguiente institución