Association of Bartonella Species with Wild and Synanthropic Rodents in Different Brazilian Biomes

dc.creatorGonçalves, Luiz Ricardo
dc.creatorFavacho, Alexsandra Rodrigues de Mendonça
dc.creatorRoque, André Luiz Rodrigues
dc.creatorMendes, Natalia Serra
dc.creatorFidelis Junior, Otávio Luiz
dc.creatorBenevenute, Jyan Lucas
dc.creatorHerrera, Heitor Miraglia
dc.creatorD'Andrea, Paulo Sérgio
dc.creatorLemos, Elba Regina Sampaio de
dc.creatorMachado, Rosangela Zacarias
dc.creatorAndré, Marcos Rogério
dc.date2017-02-16T13:06:27Z
dc.date2017-02-16T13:06:27Z
dc.date2016
dc.date.accessioned2023-09-26T22:06:17Z
dc.date.available2023-09-26T22:06:17Z
dc.identifierGONÇALVES, Luiz Ricardo; et al. Association of Bartonella Species with Wild and Synanthropic Rodents in Different Brazilian Biomes. Applied and Environmental Microbiology, v. 82, n. 24, p. 7154-7164, Dec. 2016.
dc.identifier0099-2240
dc.identifierhttps://www.arca.fiocruz.br/handle/icict/17835
dc.identifier10.1128/AEM.02447-16
dc.identifier1098-5336
dc.identifier.urihttps://repositorioslatinoamericanos.uchile.cl/handle/2250/8874787
dc.descriptionBartonella spp. comprise an ecologically successful group of microorganisms that infect erythrocytes and have adapted to different hosts, which include a wide range of mammals, besides humans. Rodents are reservoirs of about two-thirds of Bartonella spp. described to date; and some of them have been implicated as causative agents of human diseases. In our study, we performed molecular and phylogenetic analyses of Bartonella spp. infecting wild rodents from five different Brazilian biomes. In order to characterize the genetic diversity of Bartonella spp., we performed a robust analysis based on three target genes, followed by sequencing, Bayesian inference, and maximum likelihood analysis. Bartonella spp. were detected in 25.6% (117/457) of rodent spleen samples analyzed, and this occurrence varied among different biomes. The diversity analysis of gltA sequences showed the presence of 15 different haplotypes. Analysis of the phylogenetic relationship of gltA sequences performed by Bayesian inference and maximum likelihood showed that the Bartonella species detected in rodents from Brazil was closely related to the phylogenetic group A detected in other cricetid rodents from North America, probably constituting only one species. Last, the Bartonella species genogroup identified in the present study formed a monophyletic group that included Bartonella samples from seven different rodent species distributed in three distinct biomes. In conclusion, our study showed that the occurrence of Bartonella bacteria in rodents is much more frequent and widespread than previously recognized.
dc.formatapplication/pdf
dc.formatapplication/pdf
dc.languageeng
dc.publisherAmerican Society for Microbiology
dc.rightsopen access
dc.subjectBartonella
dc.subjectRoedores sinantrópicos
dc.subjectBrasil
dc.subjectBartonella bacteria
dc.subjectSynanthropic Rodents
dc.subjectBrazil
dc.titleAssociation of Bartonella Species with Wild and Synanthropic Rodents in Different Brazilian Biomes
dc.typeArticle


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