A purification methodology for viable and infective Plasmodium vivax gametocytes compatible with transmission blocking assays

dc.creatorVera, Omaira
dc.creatorBrito, Paula Brelas de
dc.creatorAlbrecht, Letusa
dc.creatorCampos, Keillen Monick Martins
dc.creatorPimenta, Paulo Filemon Paolucci
dc.creatorMonteiro, Wuelton Marcelo
dc.creatorLacerda, Marcus Vinícius Guimarães de
dc.creatorLopes, Stefanie Costa Pinto
dc.creatorCosta, Fabio Trindade Maranhão
dc.date2016-04-14T14:16:35Z
dc.date2016-04-14T14:16:35Z
dc.date2015
dc.date.accessioned2023-09-26T22:01:04Z
dc.date.available2023-09-26T22:01:04Z
dc.identifierVERA, Omaira et al. A purification methodology for viable and infective Plasmodium vivax gametocytes compatible with transmission blocking assays. Antimicrobial Agents and Chemotherapy, v. 59, n. 10, p. 6638-6641, 2015.
dc.identifier0066-4804
dc.identifierhttps://www.arca.fiocruz.br/handle/icict/13766
dc.identifier10.1128/AAC.01136-15
dc.identifier.urihttps://repositorioslatinoamericanos.uchile.cl/handle/2250/8874380
dc.descriptionSignificant progress toward the control of malaria has been achieved, especially regarding Plasmodium falciparum infections. However, the unique biology of Plasmodium vivax hampers current control strategies. The early appearance of P. vivax gametocytes in the peripheral blood and the impossibility of culturing this parasite are major drawbacks. Using blood samples from 40 P. vivax-infected patients, we describe here a methodology to purify viable gametocytes and further infect anophelines. This method opens new avenues to validate transmission-blocking strategies.
dc.formatapplication/pdf
dc.languageeng
dc.publisherAmerican Society for Microbiology
dc.rightsopen access
dc.subjectMalaria
dc.subjectPlasmodium falciparum
dc.titleA purification methodology for viable and infective Plasmodium vivax gametocytes compatible with transmission blocking assays
dc.typeArticle


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