Repeat pregnancy in women with HIV infection in Latin America and the Caribbean

dc.creatorKreitchmann, Regis
dc.creatorMegazzini, Karen
dc.creatorMelo, Victor Hugo
dc.creatorFernandes Coelho, Débora
dc.creatorWatts, D. Heather
dc.creatorKrauss, Margot
dc.creatorGouvea, Maria Isabel
dc.creatorDuarte, Geraldo
dc.creatorLosso, Marcelo H.
dc.creatorSiberry, George K.
dc.date2019-04-04T14:01:20Z
dc.date2019-04-04T14:01:20Z
dc.date2015
dc.date.accessioned2023-09-26T21:56:58Z
dc.date.available2023-09-26T21:56:58Z
dc.identifierKREITCHMANN, Regis et al. Repeat pregnancy in women with HIV infection in Latin America and the Caribbean. AIDS Care, v. 27, n. 10, p. 1289-1297, 2015.
dc.identifier0954-0121
dc.identifierhttps://www.arca.fiocruz.br/handle/icict/32363
dc.identifier10.1080/09540121.2015.1050987
dc.identifier1678-4227
dc.identifier.urihttps://repositorioslatinoamericanos.uchile.cl/handle/2250/8874148
dc.descriptionMaria Isabel Fragoso da Silveira Gouvêa. Fundação Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas. Documento produzido em parceria ou por autor vinculado à Fiocruz, mas não consta à informação no documento.
dc.descriptionIntended and unintended pregnancies occur frequently among human immunodeficiency virus (HIV)-infected women. We evaluated the occurrence of repeat pregnancy and characteristics associated with this outcome among HIV-infected women in Latin America and the Caribbean who were participating in the National Institute of Child Health and Human Development (NICHD) International Site Development Initiative (NISDI). Of the 1342 HIV-infected pregnant women enrolled in NISDI, 124 (9.2%) had one or more repeat pregnancies on study. Median time between the index delivery and date of conception of the subsequent pregnancy was 1.4 years (range 0.1-5.7). Younger age (odds ratio [OR] = 1.07, 95% confidence interval [CI]: 1.04-1.11 per one year decrease in age), hospitalization during the index pregnancy or up to six months post-partum [OR = 2.0, 95% CI: 1.2-3.4], and poor index pregnancy outcome (stillbirth or spontaneous/therapeutic abortion; OR = 3.4, 95% CI: 1.4-8.4) were associated with increased occurrence of repeat pregnancy in multivariable analysis. Among women with repeat pregnancies, the proportion receiving antiretroviral treatment (vs. prophylaxis) increased from 39.4% at the time of the index pregnancy to 81.8% at the time of the repeat pregnancy (p < 0.001). These results can help identify women most likely to benefit from reproductive counseling in order to assist with healthy pregnancy planning and prevention of unintended pregnancies.
dc.description2020-04-05
dc.formatapplication/pdf
dc.languageeng
dc.publisherAcademia Brasileira de Neurologia
dc.rightsopen access
dc.subjectHIV
dc.subjectPredictors of repeat pregnancy
dc.subjectPregnancy
dc.subjectLatin America
dc.titleRepeat pregnancy in women with HIV infection in Latin America and the Caribbean
dc.typeArticle


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