COVID-19 in patients with cardiac disease: Impact and variables associated with mortality in a cardiology center in Brazil

dc.creatorPaulino, Mariah Rodrigues
dc.creatorMoreira, José Alfredo de Sousa
dc.creatorCorreia, Marcelo Goulart
dc.creatorSantos, Léo Rodrigo Abrahão dos
dc.creatorDuarte, Ingrid Paiva
dc.creatorSabioni, Letícia Roberto
dc.creatorMucillo, Fabiana Bergamin
dc.creatorGarrido, Rafael Quaresma
dc.creatorPacheco, Stephan Lachtermacher
dc.creatorLorenzo, Andrea de
dc.creatorLamas, Cristiane da Cruz
dc.date2022-01-24T13:55:06Z
dc.date2022-01-24T13:55:06Z
dc.date2021
dc.date.accessioned2023-09-26T21:35:43Z
dc.date.available2023-09-26T21:35:43Z
dc.identifierPAULINO, Mariah Rodrigues et al. COVID-19 in patients with cardiac disease: Impact and variables associated with mortality in a cardiology center in Brazil. American Heart Journal Plus, v. 12, 100069, p. 1-7, 2021.
dc.identifier2666-6022
dc.identifierhttps://www.arca.fiocruz.br/handle/icict/50857
dc.identifier10.1016/j.ahjo.2021.100069
dc.identifier.urihttps://repositorioslatinoamericanos.uchile.cl/handle/2250/8872934
dc.descriptionSince January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
dc.descriptionBackground: Cardiovascular disease is associated with severe COVID-19. Our aim was to describe clinical and laboratory features (including electrocardiographic and echocardiographic ones) and outcomes of patients with cardiac disease hospitalized with COVID-19. Methods: This is an observational retrospective study of consecutive adult patients admitted, between March and September of 2020, with confirmed SARSCoV-2 infection. Data were collected as per the ISARIC case report form and complemented with variables related to heart disease. Results: One hundred twenty-one patients were included. Mean age was 60 SD 15.2 years and 80/121(66.1%) were male. Two-thirds of the patients (80/121, 66.1%) had COVID-19 at the time of hospital admission and COVID-19 was the reason for hospitalization in 42 (34.7%). Other reasons for hospital admission were acute coronary syndrome (26%) and decompensated heart failure (14.8%). Chronic cardiac diseases were found in 106/121 (87.6%), mostly coronary artery disease (62%) or valve disease (33.9%). A transthoracic echocardiogram was performed in 93/121(76.8%) and enlarged cardiac chambers were found in 71% (66/93); admission ECG was done in 93 cases (93/121, 76.8%), and 89.2% (83/93) were abnormal. Hospital-acquisition of COVID-19 occurred in 20 (16.5%) of patients and their mortality was 50%. On bivariate analysis for mortality, BNP levels and troponin levels were NOT associated with mortality. On multivariate analysis, only C reactive protein levels and creatinine levels were significant. Conclusions: COVID-19 impacted the profile of hospital admissions in cardiac patients. BNP and troponin levels were not associated with mortality and may not be good prognostic discriminators in cardiac patients.
dc.formatapplication/pdf
dc.languageeng
dc.publisherElsevier
dc.rightsopen access
dc.subjectCOVID-19
dc.subjectCardiac disease
dc.subjectCardiac surgery
dc.subjectCoronavirus
dc.subjectHospitalization
dc.subjectMortality
dc.titleCOVID-19 in patients with cardiac disease: Impact and variables associated with mortality in a cardiology center in Brazil
dc.typeArticle


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