Structural and ultrastructural changes in the lungs of cats Felis catus (Linnaeus, 1758) experimentally infected with D. immitis (Leidy, 1856)

dc.creatorMaia, Frederico C. L.
dc.creatorMcCall, John W.
dc.creatorSilva, Valdemiro A.
dc.creatorPeixoto, Cristina A.
dc.creatorSupakorndej, Prasit
dc.creatorSupakorndej, Nonglak
dc.creatorAlves, Leucio C.
dc.date2019-01-23T12:44:16Z
dc.date2019-01-23T12:44:16Z
dc.date2011
dc.date.accessioned2023-09-26T21:24:23Z
dc.date.available2023-09-26T21:24:23Z
dc.identifierMAIA, Frederico C. L. et al. Structural and Ultrastructural Changes in the Lungs of Cats Felis Catus (Linnaeus, 1758) Experimentally Infected with D. Immitis (Leidy, 1856). Veterinary Parasitology, v. 176, n. 4, p. 304–312, 22 mar. 2011.
dc.identifier1873-2550
dc.identifierhttps://www.arca.fiocruz.br/handle/icict/31241
dc.identifier10.1016/j.vetpar.2011.01.014
dc.identifier.urihttps://repositorioslatinoamericanos.uchile.cl/handle/2250/8872290
dc.descriptionClinical signs are seldom observed in feline heartworm disease, and the pathophysiological changes in the lungs of infected animals remain undefined. The goal of this study was to evaluate the structural and ultrastructural changes in the lungs of cats experimentally infected with Dirofilaria immitis. Six healthy cats were each infected with two adult heartworms by intravenous transplantation (Receptor Group, RG). The control group consisted of two uninfected animals kept under the same conditions as the RG. At 42 days after transplantation, all cats were euthanized and necropsied for worm recovery and collection of lung samples for examination by light microscopy (LM) and transmission electron microscopy. By LM, lung sections from the six infected cats exhibited bronchial and bronchiolar lesions. Alterations in all tissues of the pulmonary arteries were observed in the infected animals. In conclusion, cats infected experimentally with D. immitis developed lesions in their lungs as a consequence of arterial disease and intense interstitial pneumonia.
dc.description2050-01-01
dc.formatapplication/pdf
dc.languageeng
dc.rightsrestricted access
dc.subjectFeline heartworm
dc.subjectLight microscopy
dc.subjectTransmission electron microscopy
dc.subjectPathology
dc.subjectAnimais
dc.subjectDoenças do Gato / parasitologia
dc.subjectDoenças do gato / patologia
dc.subjectGatos
dc.subjectDirofilaria immitis / pathogenicity
dc.subjectDirofilariose / parasitologia
dc.subjectDirofilariose / patologia
dc.subjectPulmão / parasitologia
dc.subjectPulmão / patologia
dc.subjectPulmão / ultraestrutura
dc.subjectMicroscopia Eletrônica de Transmissão / veterinária
dc.subjectArtéria Pulmonar / parasitologia
dc.subjectArtéria Pulmonar / patologia
dc.subjectArtéria Pulmonar / ultraestrutura
dc.titleStructural and ultrastructural changes in the lungs of cats Felis catus (Linnaeus, 1758) experimentally infected with D. immitis (Leidy, 1856)
dc.typeArticle


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