Paradoxical reaction to golimumab: tumor necrosis factor α inhibitor inducing psoriasis pustulosa

dc.creatorLopes, Marien Siqueira Soto
dc.creatorTrope, Beatriz Moritz
dc.creatorRodriguez, Maria Paula Rua Rochedo
dc.creatorGrynszpan, Rachel Lima
dc.creatorCuzzi, Tullia
dc.creatorSilva, Marcia Ramos e
dc.date2015-06-29T16:43:08Z
dc.date2015-06-29T16:43:08Z
dc.date2013
dc.date.accessioned2023-09-26T21:17:13Z
dc.date.available2023-09-26T21:17:13Z
dc.identifierLOPES, Marien Siqueira Soto et al. Paradoxical reaction to golimumab: tumor necrosis factor α inhibitor inducing psoriasis pustulosa. Case Reports in Dermatology, v.5, n.3, p.326–331, 2013.
dc.identifier1662-6567
dc.identifierhttps://www.arca.fiocruz.br/handle/icict/11001
dc.identifier10.1159/000350930
dc.identifier1662-6567
dc.identifier.urihttps://repositorioslatinoamericanos.uchile.cl/handle/2250/8871887
dc.descriptionGolimumab is a human monoclonal antibody, used for rheumatoid arthritis, psoriatic arthritis and ankylosing spondylitis. Adverse reactions are increasing with this class of medication (tumor necrosis factor α inhibitors). Observations: The authors present a case of a female patient who presented with psoriasis pustulosa after the use of golimumab for rheumatoid arthritis. Conclusions and Relevance: Paradoxically, in this case, golimumab, which is used for psoriasis, induced the pustular form of this disease. We are observing an increasing number of patients who develop collateral effects with tumor necrosis factor α inhibitors, and the understanding of the mechanism of action and how these adverse reactions occur may contribute to avoid these sometimes severe situations.
dc.formatapplication/pdf
dc.languageeng
dc.publisherKarger
dc.rightsopen access
dc.subjectGolimumab
dc.subjectReação paradoxal
dc.subjectPsoriasis
dc.subjectTumor Necrosis Factor-alpha
dc.subjectImmunosuppressive Agents
dc.subjectArthritis, Rheumatoid
dc.subjectPsoríase
dc.subjectFator de Necrose Tumoral alfa
dc.subjectImunossupressores
dc.subjectArtrite Reumatoide
dc.titleParadoxical reaction to golimumab: tumor necrosis factor α inhibitor inducing psoriasis pustulosa
dc.typeArticle


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