Teratogenic effects of the Zika virus and the role of the placenta

dc.creatorAdibi, Jennifer J.
dc.creatorMarques Júnior, Ernesto Torres de Azevedo
dc.creatorCartus, Abigail
dc.creatorBeigi, Richard H.
dc.date2016-04-08T12:50:07Z
dc.date2016-04-08T12:50:07Z
dc.date2016
dc.date.accessioned2023-09-26T21:13:35Z
dc.date.available2023-09-26T21:13:35Z
dc.identifierADIBI, Jennifer J.; MARQUES JUNIOR, Ernesto Torres de Azevedo; CARTUS, Abigail; BEIGI, Richard H. Teratogenic effects of the Zika virus and the role of the placenta. The Lancet, New York, p. 2-4, 4 Mar. 2016. Disponível em: <http://thelancet.com/pdfs/journals/lancet/PIIS0140-6736(16)00650-4.pdf>. Acesso em: 04 abr. 2016.
dc.identifier0140-6736
dc.identifierhttps://www.arca.fiocruz.br/handle/icict/13657
dc.identifier10.1016/S0140-6736(16)00650-4
dc.identifier.urihttps://repositorioslatinoamericanos.uchile.cl/handle/2250/8871124
dc.descriptionArtigo liberado em acesso aberto como parte do acordo para tornar público todos os dados produzidos sobre o vírus zika - Compartilhamento de dados em emergências de saúde pública - http://www.wellcome.ac.uk/News/Media-office/Press-releases/2016/WTP060169.htm
dc.descriptionThe mechanism by which the Zika virus can cause fetal microcephaly is not known. Reports indicate that Zika is able to evade the normal immunoprotective responses of the placenta. Microcephaly has genetic causes, some associated with maternal exposures including radiation, tobacco smoke, alcohol, and viruses. Two hypotheses regarding the role of the placenta are possible: one is that the placenta directly conveys the Zika virus to the early embryo or fetus. Alternatively, the placenta itself might be mounting a response to the exposure; this response might be contributing to or causing the brain defect. This distinction is crucial to the diagnosis of fetuses at risk and the design of therapeutic strategies to prevent Zika-induced teratogenesis.
dc.formatapplication/pdf
dc.languageeng
dc.publisherElsevier
dc.rightsopen access
dc.subjectZika vírus
dc.subjectMicrocefalia
dc.subjectEpidemia
dc.subjectZika
dc.subjectZika Virus
dc.subjectMicrocephaly
dc.subjectPerigos Teratogênicos
dc.subjectZika virus
dc.subjectEpidemic
dc.titleTeratogenic effects of the Zika virus and the role of the placenta
dc.typeArticle


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