Sporothrix schenckii and Sporotrichosis

dc.creatorBarros, Mônica Bastos de Lima
dc.creatorPaes, Rodrigo de Almeida
dc.creatorSchubach, Armando Oliveira
dc.date2019-11-11T13:51:34Z
dc.date2019-11-11T13:51:34Z
dc.date2011
dc.date.accessioned2023-09-26T21:11:03Z
dc.date.available2023-09-26T21:11:03Z
dc.identifierBARROS, Mônica Bastos de Lima; PAES, Rodrigo de Almeida; SCHUBACH, Armando Oliveira. Sporothrix schenckii and sporotrichosis. Clinical Microbiology Reviews, v. 24, n. 4, p. 633-654, 2011.
dc.identifier0893-8512
dc.identifierhttps://www.arca.fiocruz.br/handle/icict/36974
dc.identifier10.1128/CMR.00007-11
dc.identifier1098-6618
dc.identifier.urihttps://repositorioslatinoamericanos.uchile.cl/handle/2250/8870480
dc.descriptionSporotrichosis, which is caused by the dimorphic fungus Sporothrix schenckii, is currently distributed throughout the world, especially in tropical and subtropical zones. Infection generally occurs by traumatic inoculation of soil, plants, and organic matter contaminated with the fungus. Certain leisure and occupational activities, such as floriculture, agriculture, mining, and wood exploitation, are traditionally associated with the mycosis. Zoonotic transmission has been described in isolated cases or in small outbreaks. Since the end of the 1990s there has been an epidemic of sporotrichosis associated with transmission by cats in Rio de Janeiro, Brazil. More than 2,000 human cases and 3,000 animal cases have been reported. In humans, the lesions are usually restricted to the skin, subcutaneous cellular tissue, and adjacent lymphatic vessels. In cats, the disease can evolve with severe clinical manifestations and frequent systemic involvement. The gold standard for sporotrichosis diagnosis is culture. However, serological, histopathological, and molecular approaches have been recently adopted as auxiliary tools for the diagnosis of this mycotic infection. The first-choice treatment for both humans and cats is itraconazole.
dc.description2019-05-11
dc.formatapplication/pdf
dc.languageeng
dc.publisherAmerican Society for Microbiology
dc.rightsopen access
dc.subjectSporothrix schenckii
dc.subjectSporotrichosis
dc.titleSporothrix schenckii and Sporotrichosis
dc.typeArticle


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