Is the Thoroughbred race-horse under chronic stress?

dc.contributorUniversidade Estadual Paulista (UNESP)
dc.creatorNogueira, G. P.
dc.creatorBarnabe, R. C.
dc.date2014-05-27T11:18:16Z
dc.date2016-10-25T18:14:38Z
dc.date2014-05-27T11:18:16Z
dc.date2016-10-25T18:14:38Z
dc.date1997-10-01
dc.date.accessioned2017-04-06T00:50:18Z
dc.date.available2017-04-06T00:50:18Z
dc.identifierBrazilian Journal of Medical and Biological Research, v. 30, n. 10, p. 1237-1239, 1997.
dc.identifier0100-879X
dc.identifierhttp://hdl.handle.net/11449/65205
dc.identifierhttp://acervodigital.unesp.br/handle/11449/65205
dc.identifier10.1590/S0100-879X1997001000016
dc.identifierS0100-879X1997001000016
dc.identifier2-s2.0-0031243338.pdf
dc.identifier2-s2.0-0031243338
dc.identifierhttp://dx.doi.org/10.1590/S0100-879X1997001000016
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/886951
dc.descriptionThoroughbred fillies were divided into three groups according to age: group 1, 7 fillies aged 1 to 2 years (G1) starting the training program; group 2, 9 fillies aged 2 to 3 years (G2) in a full training program; group 3, 8 older fillies 3 to 4 years of age (G3) training and racing. Blood samples were collected weekly from July to December. Cortisol was quantified using a solid phase DPC kit. The intra- and interassay coefficients of variation were 12.5% and 15.65% and sensitivity was 1.9 ± 0.2 nmol/ l. The semester average of cortisol levels varied between groups: G1 = 148.8 ± 6.7, G2 = 125.7 ± 5.8, G3 = 101.1 ± 5.4 nmol/l, with G3 differing statistically from the other groups. The lower cortisol levels observed in the older fillies leads us to propose that the stress stimulus, when maintained over a long period of time, may become chronic and result in a reduction of hypophyseal corticotropin-releasing hormone receptors. The secretion of endogenous opioids may also lead to low serum cortisol levels.
dc.languageeng
dc.relationBrazilian Journal of Medical and Biological Research
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectChronic stress
dc.subjectCortisol
dc.subjectExercise
dc.subjectHorses
dc.subjecthydrocortisone
dc.subjectanimal
dc.subjectanimal disease
dc.subjectanimal experiment
dc.subjectblood
dc.subjectchronic disease
dc.subjecthorse
dc.subjecthorse disease
dc.subjectstress
dc.subjectAnimals
dc.subjectChronic Disease
dc.subjectHorse Diseases
dc.subjectHydrocortisone
dc.subjectPhysical Conditioning, Animal
dc.subjectStress
dc.titleIs the Thoroughbred race-horse under chronic stress?
dc.typeOtro


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