Therapeutic effects of adipose-tissue-derived mesenchymal stromal cells and their extracellular vesicles in experimental silicosis

dc.creatorBandeira, Elga
dc.creatorOliveira, Helena
dc.creatorSilva, Johnatas D.
dc.creatorMenna-Barreto, Rubem F. S.
dc.creatorTakya, Christina M.
dc.creatorSuk, Jung S.
dc.creatorWitwer, Kenneth W.
dc.creatorPaulaitis, Michael E.
dc.creatorHanes, Justin
dc.creatorRocco, Patricia R. M.
dc.creatorMorales, Marcelo M.
dc.date2019-01-29T13:47:37Z
dc.date2019-01-29T13:47:37Z
dc.date2018
dc.date.accessioned2023-09-26T21:07:13Z
dc.date.available2023-09-26T21:07:13Z
dc.identifierBANDEIRA, Elga; et al. Therapeutic effects of adipose-tissue-derived mesenchymal stromal cells and their extracellular vesicles in experimental silicosis. Respiratory Research, v.19, n.104, 10p, 2018.
dc.identifier1465-9921
dc.identifierhttps://www.arca.fiocruz.br/handle/icict/31338
dc.identifier10.1186/s12931-018-0802-3
dc.identifier1465-993X
dc.identifier.urihttps://repositorioslatinoamericanos.uchile.cl/handle/2250/8869467
dc.descriptionSilicosis is an occupational disease that affects workers who inhale silica particles, leading to extensive lung fibrosis and ultimately causing respiratory failure. Mesenchymal stromal cells (MSCs) have been shown to exert therapeutic effects in lung diseases and represent an alternative treatment for silicosis. Recently, it has been suggested that similar effects can be achieved by the therapeutic use of extracellular vesicles (EVs) obtained from MSCs. The aim of this study was to investigate the effects of adipose-tissue-derived MSCs (AD-MSCs) or their EVs in a model of silicosis.
dc.formatapplication/pdf
dc.languageeng
dc.publisherBMC
dc.rightsopen access
dc.subjectSilicose
dc.subjectVesículas extracelulares
dc.subjectInflamação
dc.subjectFibrose
dc.subjectCélulas Mesenquimais Estromais
dc.subjectSilicosis
dc.subjectMesenchymal stromal cells
dc.subjectInflammation
dc.subjectFibrosis
dc.subjectExtracellular vesicles
dc.subjectCélulas Mesenquimais Estromais
dc.titleTherapeutic effects of adipose-tissue-derived mesenchymal stromal cells and their extracellular vesicles in experimental silicosis
dc.typeArticle


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