Transmission blocking sugar baits for the control of Leishmania development inside sand flies using environmentally friendly beta-glycosides and their aglycones

dc.creatorFerreira, Tainá Neves
dc.creatorPereira, Daniela Pita
dc.creatorCosta, Samara Graciane
dc.creatorBrazil, Reginaldo Peçanha
dc.creatorMoraes, Caroline Silva
dc.creatorDíaz-Albiter, Hector Manuel
dc.creatorGenta, Fernando Ariel
dc.date2019-01-22T11:18:03Z
dc.date2019-01-22T11:18:03Z
dc.date2018
dc.date.accessioned2023-09-26T21:06:26Z
dc.date.available2023-09-26T21:06:26Z
dc.identifierFERREIRA, Tainá Neves; et al. Transmission blocking sugar baits for the control of Leishmania development inside sand flies using environmentally friendly beta-glycosides and their aglycones. Parasites & Vectors, v.11, n.614, 20p, 2018.
dc.identifier1756-3305
dc.identifierhttps://www.arca.fiocruz.br/handle/icict/31205
dc.identifier10.1186/s13071-018-3122-z
dc.identifier.urihttps://repositorioslatinoamericanos.uchile.cl/handle/2250/8869253
dc.descriptionThe sand fly Lutzomyia longipalpis is the main vector of American visceral leishmaniasis, a disease caused by parasites of the genus Leishmania. Adults of this insect feed on blood (females only) or sugar from plant sources, but their digestion of carbohydrates is poorly studied. Beta-glycosides as esculin and amygdalin are plant compounds and release toxic compounds as esculetin and mandelonitrile when hydrolyzed. Beta-glucosidase and trehalase are essential enzymes in sand fly metabolism and participate in sugar digestion. It is therefore possible that the toxic portions of these glycosides, released during digestion, affect sand fly physiology and the development of Leishmania.
dc.formatapplication/pdf
dc.languageeng
dc.publisherBMC
dc.rightsopen access
dc.subjectLutzomyia longipalpis
dc.subjectLeishmania
dc.subjectbeta-Glucosidase
dc.subjectTrealase
dc.subjectLongevidade
dc.subjectIsca de açucar
dc.subjectLutzomyia longipalpis
dc.subjectLeishmania
dc.subjectLongevity
dc.subjectBeta-glycosides
dc.subjectTrehalase
dc.subjectBeta-glucosidase
dc.subjectSugar bait
dc.titleTransmission blocking sugar baits for the control of Leishmania development inside sand flies using environmentally friendly beta-glycosides and their aglycones
dc.typeArticle


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