Study of hantavirus infection in captive breed colonies of wild rodents

dc.creatorOliveira, R. C.
dc.creatorRozental, T.
dc.creatorCorrêa, A. A. Alves
dc.creatorD`Andrea, P. S.
dc.creatorSchatzmayr, H.
dc.creatorCerqueira, R.
dc.creatorLemos, Elba Regina S.
dc.date2020-11-19T17:23:26Z
dc.date2020-11-19T17:23:26Z
dc.date2004
dc.date.accessioned2023-09-26T21:05:53Z
dc.date.available2023-09-26T21:05:53Z
dc.identifierOLIVEIRA, R. C. et al. Study of hantavirus infection in captive breed colonies of wild rodents. Memórias do Instituto Oswaldo Cruz, Rio de Janeiro, v. 99, n. 6, p. 575-576, Oct. 2004.
dc.identifier0074-0276
dc.identifierhttps://www.arca.fiocruz.br/handle/icict/44542
dc.identifier10.1590/S0074-02762004000600007
dc.identifier1678-8060
dc.identifier.urihttps://repositorioslatinoamericanos.uchile.cl/handle/2250/8869100
dc.descriptionWild sigmondontine rodents are known to be the reservoir of several serotypes of New World hantaviruses. The mechanism of viral transmission is by aerosol inhalation of the excreta from infected rodents. Considering that the captive breed colonies of various wild mammals may present a potencial risk for hantaviral transmission, we examined 85 speciemens of Thrichomys spp. (Echimyidae) and 17 speciemens of Nectomys squamipes (Sigmodontinae) from our colony for the presence of hantavirus infections. Blood samples were assayed for the presence of antibodies to Andes nucleocapsid antigen using enzyme-linked immunosorbent assay (ELISA). Additionally, serum samples from workers previously exposed to wild rodents, in the laboratories where the study was conducted, were also tested by ELISA to investigate prevalence of anti-hantavirus IgG antibodies. All blood samples were negative for hantavirus antibodies. Although these results suggest that those rodent’s colonies are hantavirus free, the work emphasizes the need for hantavirus serological monitoring in wild colonized rodents and secure handling potentially infected rodents as important biosafety measures.
dc.formatapplication/pdf
dc.languageeng
dc.publisherFundação Oswaldo Cruz. Instituto Oswaldo Cruz.
dc.rightsopen access
dc.subjectHantavírus
dc.subjectRoedores
dc.subjectSíndrome cardiopulmonar do hantavírus
dc.subjectHantaviruses
dc.subjectRodents
dc.subjectHantavirus cardiopulmonary syndrome (HPS)
dc.titleStudy of hantavirus infection in captive breed colonies of wild rodents
dc.typeArticle


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