| dc.creator | Parolin, Cristina | |
| dc.creator | Virtuoso, Sara | |
| dc.creator | Giovanetti, Marta | |
| dc.creator | Angeletti, Silvia | |
| dc.creator | Ciccozzi, Massimo | |
| dc.creator | Borsetti, Alessandra | |
| dc.date | 2022-02-23T11:15:14Z | |
| dc.date | 2022-02-23T11:15:14Z | |
| dc.date | 2021 | |
| dc.date.accessioned | 2023-09-26T21:04:31Z | |
| dc.date.available | 2023-09-26T21:04:31Z | |
| dc.identifier | PAROLIN, Cristina et al. Animal Hosts and Experimental Models of SARS-CoV-2 Infection. Chemotherapy, p. 1 - 9. 2021. | |
| dc.identifier | 0009-3157 | |
| dc.identifier | https://www.arca.fiocruz.br/handle/icict/51423 | |
| dc.identifier | 10.1159/000515341 | |
| dc.identifier.uri | https://repositorioslatinoamericanos.uchile.cl/handle/2250/8868736 | |
| dc.description | Viruses arise through cross-species transmission and can
cause potentially fatal diseases in humans. This is the case of
the severe acute respiratory syndrome coronavirus 2 (SARSCoV-
2) which recently appeared in Wuhan, China, and rapidly
spread worldwide, causing the outbreak of coronavirus
disease 2019 (COVID-19) and posing a global health emergency.
Sequence analysis and epidemiological investigations
suggest that the most likely original source of SARSCoV-
2 is a spillover from an animal reservoir, probably bats,
that infected humans either directly or through intermediate
animal hosts. The role of animals as reservoirs and natural
hosts in SARS-CoV-2 has to be explored, and animal models
for COVID-19 are needed as well to be evaluated for countermeasures
against SARS-CoV-2 infection. Experimental cells,
tissues, and animal models that are currently being used and
developed in COVID-19 research will be presented. | |
| dc.format | application/pdf | |
| dc.language | eng | |
| dc.publisher | Karger | |
| dc.rights | open access | |
| dc.subject | Síndrome respiratória aguda grave coronavírus 2 | |
| dc.subject | Hospedeiros de animais | |
| dc.subject | Modelos animais | |
| dc.subject | Modelos de células | |
| dc.subject | Severe acute respiratory syndrome coronavirus 2 | |
| dc.subject | Animal hosts | |
| dc.subject | Animal models | |
| dc.subject | Cell models | |
| dc.title | Animal Hosts and Experimental Models of SARS-CoV-2 Infection | |
| dc.type | Article | |
