Paleoparasitology of Chagas disease - A Review

dc.creatorAraújo, Adauto
dc.creatorJansen, Ana Maria
dc.creatorReinhard, Karl
dc.creatorFerreira, Luiz Fernando
dc.date2017-08-31T11:36:34Z
dc.date2017-08-31T11:36:34Z
dc.date2009
dc.date.accessioned2023-09-26T21:04:20Z
dc.date.available2023-09-26T21:04:20Z
dc.identifierARAÚJO, Adauto; et al. Paleoparasitology of Chagas disease - A Review. Mem Inst Oswaldo Cruz, Rio de Janeiro, Vol. 104, Suppl. I, p. 9-16, 2009.
dc.identifier0074-0276
dc.identifierhttps://www.arca.fiocruz.br/handle/icict/20845
dc.identifier1678-8060
dc.identifier.urihttps://repositorioslatinoamericanos.uchile.cl/handle/2250/8868683
dc.descriptionOne hundred years since the discovery of Chagas disease associated with Trypanosoma cruzi infection, growing attention has focused on understanding the evolution in parasite-human host interaction. This interest has featured studies and results from paleoparasitology, not only the description of lesions in mummified bodies, but also the recovery of genetic material from the parasite and the possibility of analyzing such material over time. The present study reviews the evidence of Chagas disease in organic remains excavated from archeological sites and discusses two findings in greater detail, both with lesions suggestive of chagasic megacolon and confirmed by molecular biology techniques. One of these sites is located in the United States, on the border between Texas and Mexico and the other in state of Minas Gerais, in the Brazilian cerrado (savannah). Dated prior to contact with Europeans, these results confirm that Chagas disease affected prehistoric human groups in other regions outside the Andean altiplanos and other transmission areas on the Pacific Coast, previously considered the origin of T. cruzi infection in the human host.
dc.formatapplication/pdf
dc.languageeng
dc.publisherFundação Oswaldo Cruz. Instituto Oswaldo Cruz
dc.rightsopen access
dc.subjectTrypanosoma cruzi
dc.subjectPaleoparasitologia
dc.subjectPaleoepidemiologia
dc.subjectDNA antigo
dc.subjectMúmias
dc.subjectpaleoparasitology
dc.subjectpaleoepidemiology
dc.subjectChagas Disease
dc.subjectancient DN
dc.subjectmummies
dc.subjectTrypanosoma cruzi.
dc.titlePaleoparasitology of Chagas disease - A Review
dc.typeArticle


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