Distribution of glutathione S-transferase GSTM1 and GSTT1 null phenotypes in Brazilian Amerindians

dc.creatorGuimarães, Maria de Nazaré Klautau
dc.creatorHiragi, Cássia de Oliveira
dc.creatorD`Ascenção, Renata Ferreira
dc.creatorOliveira, Silviene Fabiana
dc.creatorGrisolia, Cesar Kopke
dc.creatorHatagima, Ana
dc.creatorFerrari, Íris
dc.date2019-12-10T12:46:15Z
dc.date2019-12-10T12:46:15Z
dc.date2005
dc.date.accessioned2023-09-26T21:02:07Z
dc.date.available2023-09-26T21:02:07Z
dc.identifierGUIMARÃES, Maria de Nazaré Klatau et al. Distribution of glutathione S-transferase GSTM1 and GSTT1 null phenotypes in Brazilian Amerindians. Genetics and Molecular Biology, São Paulo, v. 28, n. 1, p. 33-35, 2005.
dc.identifier1415-4757
dc.identifierhttps://www.arca.fiocruz.br/handle/icict/37738
dc.identifier10.1590/S1415-47572005000100005
dc.identifier1678-4685
dc.identifier.urihttps://repositorioslatinoamericanos.uchile.cl/handle/2250/8868086
dc.descriptionThe distribution of glutathione S-transferase (GST) GSTM1 and GSTT1 null phenotype frequencies in two Brazilian Amerindian tribes, the Munduruku tribe from Missão Cururu village (79 individuals) and the Kayabi tribe (41 individuals), was analyzed by polymerase chain reaction (PCR) amplification. The GST null phenotype frequencies for the Munduruku sample were 0% for GSTM1 and 27% for GSTT1 while for the Kayabi sample the null phenotype frequencies were 27% for GSTM1 and 29% for GSTT1. This is the first report of the absence of the GSTM1 null phenotype in any ethnic group.
dc.formatapplication/pdf
dc.languageeng
dc.publisherSociedade Brasileira de Genética
dc.rightsopen access
dc.subjectMunduruku
dc.subjectKayabi
dc.subjectAlelos nulos
dc.subjectGlutationa S-transferase
dc.subjectMunduruku
dc.subjectGlutathione S-transferase
dc.subjectKayabi
dc.subjectNull alleles
dc.titleDistribution of glutathione S-transferase GSTM1 and GSTT1 null phenotypes in Brazilian Amerindians
dc.typeArticle


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