The Use of Bioinformatics for Studying HIV Evolutionary and Epidemiological History in South America

dc.creatorBello, Gonzalo
dc.creatorSoares, Marcelo A.
dc.creatorSchrago, Carlos G.
dc.date2016-09-20T17:12:17Z
dc.date2016-09-20T17:12:17Z
dc.date2011
dc.date.accessioned2023-09-26T21:01:52Z
dc.date.available2023-09-26T21:01:52Z
dc.identifierBELLO, Gonzalo; SOARES, Marcelo A.; SCHRAGO, Carlos G. The Use of Bioinformatics for Studying HIV Evolutionary and Epidemiological History in South America. AIDS Research and Treatment, v.2011, Article ID 154945, 13p, 2011.
dc.identifier2090-1240
dc.identifierhttps://www.arca.fiocruz.br/handle/icict/15873
dc.identifier10.1155/2011/154945
dc.identifier2090-1259
dc.identifier.urihttps://repositorioslatinoamericanos.uchile.cl/handle/2250/8868014
dc.descriptionThe South American human immunodeficiency virus type 1 (HIV-1) epidemic is driven by several subtypes (B, C, and F1) and circulating and unique recombinant forms derived from those subtypes. Those variants are heterogeneously distributed around the continent in a country-specific manner. Despite some inconsistencies mainly derived from sampling biases and analytical constrains, most of studies carried out in the area agreed in pointing out specificities in the evolutionary dynamics of the circulating HIV-1 lineages. In this paper, we covered the theoretical basis, and the application of bioinformatics methods to reconstruct the HIV spatial-temporal dynamics, unveiling relevant information to understand the origin, geographical dissemination and the current molecular scenario of the HIV epidemic in the continent, particularly in the countries of Southern Cone.
dc.formatapplication/pdf
dc.languageeng
dc.publisherHindawi Publishing Corporation
dc.rightsopen access
dc.subjectHIV-1
dc.subjectAmérica do Sul
dc.subjectBioinformática
dc.subjectHistória epidemiológica
dc.subjectHuman immunodeficiency virus type 1 (HIV-1)
dc.subjectSouth America
dc.subjectBioinformatics
dc.subjectEpidemiological History
dc.titleThe Use of Bioinformatics for Studying HIV Evolutionary and Epidemiological History in South America
dc.typeArticle


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