dc.creator | Santos, Luciano Cincurá Silva | |
dc.creator | Ramos, Eduardo Antônio Gonçalves | |
dc.creator | Gurgel, Clarissa Araújo Silva | |
dc.creator | Santana, Edmar José Borges de | |
dc.creator | Santos, Jean Nunes dos | |
dc.date | 2015-05-05T17:36:10Z | |
dc.date | 2015-05-05T17:36:10Z | |
dc.date | 2007 | |
dc.date.accessioned | 2023-09-26T21:01:52Z | |
dc.date.available | 2023-09-26T21:01:52Z | |
dc.identifier | SANTOS, L. C. et al. Immunohistochemical detection of Langerhans cells in dental granulomas and radicular cysts. Journal of Molecular Histology, v. 38, n. 3, p. 201-205, 2007. | |
dc.identifier | 1567-2379 | |
dc.identifier | https://www.arca.fiocruz.br/handle/icict/10243 | |
dc.identifier | 10.1007/s10735-007-9088-3 | |
dc.identifier.uri | https://repositorioslatinoamericanos.uchile.cl/handle/2250/8868013 | |
dc.description | Objective Dental granulomas (DGs) and radicular cysts
(RCs) are chronic periapical lesions frequently involving
the jaws. Langerhans cells (LCs) are dendritic cells
responsible for the presentation of antigens to T lymphocytes.
This study examined the expression of LCs in DG
and RCs by immunohistochemical staining.
Study Design Eighteen cases of DGs and 26 cases of RCs
were analyzed using anti-CD1a marker.
Results CD1a-labeled LCs were observed in 11.1% of
DGs and in 69.2% of RCs, showing a significant correlation
(P < 0.0001; Fisher’s test). In DGs, LCs were only
observed in granulation tissue, showing discrete immunostaining
density. In RCs, LCs exhibited both a round and a
dendritic shape in all epithelial layers. Although a correlation
was observed between immunostaining density and
epithelial thickness, as well as between immunostaining
and inflammatory intensity, the differences were not significant
in radicular cysts. | |
dc.format | application/pdf | |
dc.language | eng | |
dc.publisher | Springer Verlag | |
dc.rights | open access | |
dc.subject | Radicular cyst | |
dc.subject | Dental granuloma | |
dc.subject | Immunohistochemistry | |
dc.subject | Langerhans cell | |
dc.subject | Células de Langerhans/imunologia | |
dc.subject | Granuloma Periapical/imunologia | |
dc.subject | Cisto Radicular/imunologia | |
dc.subject | Adolescente | |
dc.subject | Adulto | |
dc.subject | Idoso | |
dc.subject | Antígenos CD1/imunologia | |
dc.subject | Criança | |
dc.subject | Pré-Escolar | |
dc.subject | Femenino | |
dc.subject | Humanos | |
dc.subject | Imuno-Histoquímica | |
dc.subject | Masculino | |
dc.subject | Meia-Idade | |
dc.subject | Granuloma Periapical/patologia | |
dc.subject | Cisto Radicular/patologia | |
dc.title | Immunohistochemical detection of Langerhans cells in dental granulomas and radicular cysts. | |
dc.type | Article | |