Nausea e vomito em laparoscopia ginecologica: Efeitos do oxido nitroso e da metoclopramida

dc.contributorUniversidade Estadual Paulista (UNESP)
dc.creatorGanem, Eliana Marisa
dc.creatorAchoa, R. V.
dc.creatorVianna, Pedro Thadeu Galvão
dc.creatorCastiglia, Yara Marcondes Machado
dc.date2014-05-27T11:18:11Z
dc.date2016-10-25T18:14:17Z
dc.date2014-05-27T11:18:11Z
dc.date2016-10-25T18:14:17Z
dc.date1997-01-01
dc.date.accessioned2017-04-06T00:48:56Z
dc.date.available2017-04-06T00:48:56Z
dc.identifierRevista Brasileira de Anestesiologia, v. 47, n. 6, p. 512-521, 1997.
dc.identifier0034-7094
dc.identifierhttp://hdl.handle.net/11449/65014
dc.identifierhttp://acervodigital.unesp.br/handle/11449/65014
dc.identifier2-s2.0-0030833006.pdf
dc.identifier2-s2.0-0030833006
dc.identifierhttp://www.sba.com.br/arquivos/revista/rba/nov97512.pdf
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/886778
dc.descriptionBackground and Objectives - Gynecological laparoscopy causes high postoperative morbidity, mainly due to occurrences such as nausea and vomiting. They result from a great multiplicity of etiologies and drugs used in anesthesia may function as contributing factors. Both the emetic properties of nitrous oxide and the efficacy of metoclopramide as antiemetic agent are controversial. This study was undertaken to determine the effects of both drugs, when used alone or in combination. Methods - Eighty three physical status ASA I and II women were studied. They were premedicated with midazolam before induction of anesthesia with alfentanil and propofol. Anesthesia was maintained with isoflurane with or without nitrous oxide in oxygen. Muscle relaxation was achieved with atracurium. There were 4 groups of patients: GI: midazolam, alfentanil, propofol, atracurium, isoflurane/oxygen; GII: midazolam, alfentanil, propofol, atracurium, isoflurane/nitrous oxide/oxygen; GIII: metoclopramide, midazolam, alfentanil, propofol, atracurium, isoflurane/oxygen; GIV: metoclopramide, midazolam, alfentanil, propofol, atracurium, isoflurane/nitrous oxide/oxygen. The incidence of nausea and vomiting was assessed both in the recovery room (RR) and in the ward. Results - There were no significant differences as regards age, weight and height of the patients and duration of anesthesia and surgery. Nausea and vomiting were more frequent in patients who received N2O (GII, 50%; GIV, 33%), as compared to those who didn't receive this agent (GI and GII, 9.5% and 14.35%, respectively). Metoclopramide decreased the incidence of nausea and vomiting in the recovery room, in patients who didn't receive N2O (GII). These patients remained in the recovery room for 90 minutes. Conclusions - N2O increases the incidence of nausea and vomiting and metoclopramide is effective in reducing these complications only in the recovery room.
dc.languagepor
dc.relationRevista Brasileira de Anestesiologia
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectAnesthetics: nitrous oxide
dc.subjectAntiemetics: metoclopramide
dc.subjectComplications: nausea, vomiting
dc.subjectSurgery: laparoscopy
dc.subjectalfentanil
dc.subjectantiemetic agent
dc.subjectatracurium
dc.subjectinhalation anesthetic agent
dc.subjectisoflurane
dc.subjectmetoclopramide
dc.subjectmidazolam
dc.subjectnitrous oxide
dc.subjectpropofol
dc.subjectadult
dc.subjectfemale
dc.subjecthuman
dc.subjectlaparoscopy
dc.subjectmajor clinical study
dc.subjectmuscle relaxation
dc.subjectnausea
dc.subjectoral drug administration
dc.subjectvomiting
dc.titleNausea e vomito em laparoscopia ginecologica: Efeitos do oxido nitroso e da metoclopramida
dc.typeOtro


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